Abstract
Unstable angina pectoris (UAP) is categorized with the Braunwald classification. However, the association of clinical presentation and plaque structure/function has not yet been elucidated in relation to cause. We used optical coherence tomography to investigate this relation. One hundred fifteen patients with primary UAP were categorized according to the Braunwald classification. Patients with class I UAP had the highest frequency of ulcers without fibrous cap disruption (p = 0.003) and the smallest minimum lumen area (class I, median 0.70 mm(2), quartiles 1 to 3 0.42 to 1.00; class II, 1.80 mm(2), 1.50 to 2.50; class III, 2.31 mm(2), 1.21 to 3.00; p <0.001). Patients with class II UAP had the highest frequency of coronary spasm (p <0.001) and the lowest frequency of thrombi (p <0.001). Patients with class III UAP had the highest frequency of plaque ruptures (p <0.001), the thinnest fibrous cap (class I, median 140 microm, quartile 1 to 3 90 to 160; class II, 150 microm, 120 to 160; class III, 60 microm, 40 to 105; p <0.001), and the highest frequency of thin cap fibroatheromas (p <0.001) and spotty calcifications (p <0.001). In conclusion, the structures/functions of culprit lesions on optical coherence tomograms differ in th...Continue Reading
References
May 1, 1995·Journal of the American College of Cardiology·A J van Miltenburg-van ZijlP M Bossuyt
Jan 15, 1996·The American Journal of Cardiology·S De ServiG Specchia
Mar 15, 1996·Circulation·M E BrezinskiJ G Fujimoto
Mar 1, 1997·Journal of the American College of Cardiology·G DangasJ A Ambrose
Aug 1, 1997·Angiology·M OwaM Saito
Sep 1, 1997·Journal of the American College of Cardiology·C DepréX Havaux
Nov 24, 1998·Circulation·E Braunwald
Jul 6, 2000·Circulation·C W Hamm, E Braunwald
Feb 19, 2002·Journal of the American College of Cardiology·Ik-Kyung JangGuillermo J Tearney
Sep 25, 2002·Circulation·Hiroshi YabushitaGuillermo J Tearney
Oct 8, 2003·Circulation·Morteza NaghaviJames T Willerson
Nov 24, 2004·Circulation·Shoichi EharaMakiko Ueda
Mar 23, 2005·Circulation·Ik-Kyung JangBrett E Bouma
Jan 24, 2006·Atherosclerosis·Ilke SipahiSteven E Nissen
Apr 8, 2006·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Mehmet CilingirogluMarc D Feldman
Apr 18, 2006·The American Journal of Cardiology·Teruyoshi KumeKiyoshi Yoshida
Jun 13, 2006·The American Journal of Cardiology·Teruyoshi KumeKiyoshi Yoshida
Sep 4, 2007·Journal of the American College of Cardiology·Takashi KuboTakashi Akasaka
Nov 19, 2008·Circulation·Atsushi TanakaTakashi Akasaka
Nov 26, 2008·Expert Review of Medical Devices·Takashi Kubo, Takashi Akasaka
Citations
May 11, 2012·European Heart Journal Cardiovascular Imaging·Yoshiki MatsuoTakashi Akasaka
Jun 15, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Yasumi UchidaNobuyuki Hiruta
Sep 24, 2011·Cardiology Research and Practice·Takashi KuboTakashi Akasaka
Jul 15, 2015·The International Journal of Cardiovascular Imaging·Charis CostopoulosMartin R Bennett
Jan 23, 2016·Radiology Research and Practice·Sunny GoelOn Chen
Jun 28, 2013·Thrombosis and Haemostasis·Gian Marco RosaFabrizio Montecucco
May 25, 2013·Annals of the New York Academy of Sciences·Troy C SarichPeter M DiBattiste
Nov 9, 2011·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Glenn N LevineUNKNOWN Society for Cardiovascular Angiography and Interventions
Feb 26, 2015·European Heart Journal·Giampaolo NiccoliFilippo Crea
Nov 11, 2011·Journal of the American College of Cardiology·Glenn N LevineUNKNOWN Society for Cardiovascular Angiography and Interventions
Nov 19, 2011·Journal of the American College of Cardiology·Robert P Giugliano, Eugene Braunwald
Jun 18, 2010·Journal of cardiology·Takashi AkasakaToshio Imanishi
Jun 22, 2016·Heart and Vessels·Mikumo SakaguchiKenei Shimada
Oct 29, 2015·European Heart Journal Cardiovascular Imaging·Mario IannacconeFiorenzo Gaita
Jul 28, 2016·International Journal of Molecular Sciences·Shoichi EharaKenei Shimada
Nov 9, 2011·Circulation·Glenn N LevineHenry H Ting
Dec 4, 2014·Expert Review of Cardiovascular Therapy·Adam J BrownMartin R Bennett
Mar 21, 2021·Cardiovascular Intervention and Therapeutics·Yoshiaki MitsutakeTakafumi Ueno
May 18, 2021·Biomedical Optics Express·Zeinab HajjarianSeemantini K Nadkarni