PMID: 6172192Jan 15, 1982Paper

Clinical classification of hepatoma in Japan according to serial changes in serum alpha-fetoprotein levels

Cancer
Y MatsumotoI Honjo

Abstract

Quantitative determinations of serum alpha-fetoprotein (AFP) in 96 patients with hepatomas have demonstrated three main groups based on changes in the serial levels: 1) patients with more than 10 000 ng/ml during most of their clinical course, and with an increase of 10 000 ng/ml or more in a week (Group A); 2) patients with levels varying from 200 to 10 000 ng/ml and with an increase of 1000 ng/ml in three to four months (Group B); and 3) patients with serum AFP level below 200 ng/ml during most of their clinical course (Group C). The patients in Group A had a mean survival time of 7.62 +/- 3.97 months, and those in Group B, 16.18 +/- 12.18 months. The patients in Group C were subdivided into two groups according to whether survival time was long (33.92 +/- 28.22 months) or short (3.75 +/- 0.87 months). Histologic findings revealed poorly differentiated carcinoma in patients in Group A, moderately differentiated carcinoma in those in Group B, and well differentiated carcinoma in those with long survival in Group C and anaplastic carcinoma in those with short survival in Group C.

Citations

Jan 1, 1993·Journal of Surgical Oncology. Supplement·H J Wanebo, M P Vezeridis
Jan 1, 1989·Cancer Chemotherapy and Pharmacology·J TanakaS Minematsu
Jan 1, 1988·Digestive Diseases and Sciences·A MaringhiniL Pagliaro
Oct 14, 1983·Clinica Chimica Acta; International Journal of Clinical Chemistry·K HuseG Kopperschläger
Jul 26, 2002·Clinical Imaging·Shashi Bala Paul, Manpreet Singh Gulati
Jun 1, 1990·Gut·R C AyresC L Smith
Sep 10, 2009·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Tanios Bekaii-SaabMiguel Villalona-Calero
Sep 15, 2005·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Khaled M ElsayesJeffrey J Brown
Mar 12, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·A NanashimaTakeshi Nagayasu
Oct 19, 2010·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Luigi AddarioGiovan Giuseppe Di Costanzo
Apr 12, 2008·Clinica Chimica Acta; International Journal of Clinical Chemistry·Xu WangJin-Ming Lin
Dec 7, 2007·Seminars in Roentgenology·Lisa H Lowe
Mar 22, 2006·International Journal of Cancer. Journal International Du Cancer·Patrizia PontissoLiliana Chemello
Jan 17, 2013·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Toshiya KamiyamaSatoru Todo
Mar 1, 1985·The American Journal of Medicine
Mar 1, 1988·Cancer Treatment Reviews·S R NerenstoneM A Friedman
Aug 1, 1987·Journal of Surgical Oncology·D A GeerJ L Berenberg
Jan 1, 1983·Journal of Surgical Oncology·Y T Lee
Apr 1, 1998·Radiologic Clinics of North America·M P Fernandez, R D Redvanly
Jun 29, 2001·Clinical Radiology·P M Kelly, F W Poon
Jul 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·L BarbaraA Mazziotti
Jul 1, 1991·Digestive Diseases and Sciences·F MarottaS C Zhang
Apr 13, 2001·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S A HussainD J Kerr

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