Clinical codes combined with procedure codes increase diagnostic accuracy of Crohn's disease in a US Military health record.

BMJ Open Gastroenterology
Manish SinglaSteven Brant

Abstract

Previous examinations of International Classification of Disease, Ninth Revision, Clinical Modification (ICD-9-CM) codes to predict accuracy of diagnosis in inflammatory bowel disease have had limited chart review to confirm diagnosis. We aimed to evaluate using the ICD-9-CM for identifying Crohn's disease (CD) in a large electronic health record (EHR) database. This is a retrospective case-control study with a 3:1 allocation of EHRs of active duty service members diagnosed with CD from 1996 to 2012. Subjects were selected by having two ICD-9-CM codes for CD during the study period. Gastroenterologists reviewed each chart and confirmed the diagnosis of CD by analysing medication history and clinical, endoscopic, histological, and radiographic exams. 300 cases of CD were selected; 14 cases were discarded due to lack of data, limiting our analysis to 284 subjects. Two diagnostic codes for CD had sensitivity, specificity, and positive predictive value (PPV) of 1.0, 0.53, and 0.69, respectively, for confirmed CD. If two encounters listing CD were with a gastroenterologist, the sensitivity, specificity, and PPV was 0.76, 0.81, and 0.80, respectively. If a colonoscopy was performed within 90 days of any three encounters with a CD cod...Continue Reading

References

Jun 8, 2002·Pharmacoepidemiology and Drug Safety·James D LewisBrian L Strom
Dec 25, 2009·Digestive Diseases and Sciences·Selvi ThirumurthiNeena S Abraham
Oct 13, 2012·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·Ali RezaieRobert J Hilsden
Nov 13, 2013·Inflammatory Bowel Diseases·Jessie P BuckleySuzanne F Cook
Apr 9, 2016·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Siddharth SinghEdward V Loftus
Nov 1, 2016·Scandinavian Journal of Gastroenterology·Gustav L JakobssonJonas F Ludvigsson

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