PMID: 19927726Nov 26, 2009Paper

Clinical comparison of propofol and remifentanil anaesthesia with sevoflurane and remifentanil anaesthesia for children with cleft lip and palate repair surgery

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
Xiao-qian DengYang Ji

Abstract

To compare the clinical effects and safety of propofol and remifentanil anaesthesia with sevoflurane and remifentanil anaesthesia for cleft lip and palate repair surgery in children. Forty children undergoing elective cleft lip and palate repair surgery were randomly divided into two groups, 20 in each group. Group PR: Propofol and remifentanil anaesthesia; and group S: Sevoflurane and remifentanil anaesthesia. Heart rate (HR), mean arterial pressure (MAP), pulse oxygen saturation (SPO2), and end tidal carbon dioxide (ETCO2) were observed, and recorded at the time before the induction (T0), after 15 min of induction (T1), after 30 min of induction (T2), and after 1 min of extubation (T3). The time to extubation, incidence of restlessness, postoperative nausea and vomiting, and the complication of the airway were recorded. There were no significantly differences between the two groups with respect to sex, age, weight, category of operation, and the time of operation. In group PR, after the period of induction, two children used atropine for bradycardia. One was 3-years-old, and the other was 8-years-old. The HR of former was lower than 100 beats per minute, and the latter was lower than 70 beats per minute. The average of HR in ...Continue Reading

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