Clinical contributions of 64-slice computed tomography in the evaluation of cardiomyopathy of unknown origin

Archives of Cardiovascular Diseases
Dominique BoulmierHervé Le Breton

Abstract

Meta-analyses have confirmed the high performance of multislice computed tomography (MSCT) in coronary stenosis detection. Recent reports have described the study of left ventricular anatomy and function and coronary venous anatomy with MSCT. We sought to compare, in patients with cardiomyopathy of unknown origin, the performance of MSCT versus angiography for significant coronary artery disease detection and versus transthoracic echocardiography (TTE) for left ventricular anatomy and function evaluation, and to assess its ability to characterize coronary venous anatomy. Fifty-nine patients with cardiomyopathy (left ventricular ejection fraction [LVEF] less than or equal to 40%) of unknown origin, in sinus rhythm, underwent MSCT, TTE and coronary angiography. Twenty-four (3%) of 724 analysable coronary segments (97%) and 12 (20%) patients had significant coronary artery disease. MSCT sensitivity, specificity, and positive and negative predictive values for coronary artery disease detection were 87.5%, 98.5%, 67.7% and 99.6% in the per-segment assessment and 100%, 91%, 75% and 100% in the per-patient evaluation, respectively. Statistical analyses showed good agreement between MSCT and TTE in LVEF measurement (33+/-10% vs 32+/-11...Continue Reading

References

Mar 22, 2001·The New England Journal of Medicine·S CazeauUNKNOWN Multisite Stimulation in Cardiomyopathies (MUSTIC) Study Investigators
Jan 15, 2002·Journal of the American College of Cardiology·G Michael FelkerChristopher M O'Connor
May 16, 2003·The New England Journal of Medicine·Mariell Jessup, Susan Brozena
Sep 1, 2005·European Radiology·Kai Uwe Juergens, Roman Fischbach
Aug 22, 2006·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Maureen M HennemanJeroen J Bax
Sep 22, 2006·European Journal of Radiology·Jean-Christophe CornilyJacques Boschat
Feb 24, 2007·European Radiology·Jean-François Paul, Hicham T Abada
May 12, 2007·International Journal of Cardiology·Luc ChristiaensJoseph Allal
May 22, 2007·Journal of the American College of Cardiology·Daniele AndreiniPiergiuseppe Agostoni
Jul 20, 2007·JAMA : the Journal of the American Medical Association·Andrew J EinsteinSanjay Rajagopalan
Dec 20, 2007·European Heart Journal·Lars HusmannPhilipp A Kaufmann
Mar 8, 2008·Clinical Radiology·T J WilliamsC A Roobottom
Apr 4, 2008·European Heart Journal·Saïd GhostineJean-François Paul
Jun 20, 2008·Cardiology in Review·Prabhakaran GopalakrishnanTahir Tak
Aug 9, 2008·European Journal of Radiology·Thomas S KristensenHenning Kelbaek

❮ Previous
Next ❯

Citations

Feb 18, 2011·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Sabha BhattiYukitaka Shizukuda
Nov 17, 2009·Archives of Cardiovascular Diseases·Christophe Caussin
Jul 8, 2020·Current Cardiology Reports·Kameel KassabRami Doukky

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.