Clinical correlates and outcomes in a group of Puerto Ricans with systemic lupus erythematosus hospitalized due to severe infections

SAGE Open Medicine
Patricia Jordán-GonzálezL M Vilá

Abstract

Infections are a major cause of morbidity and mortality in systemic lupus erythematosus. Clinical outcomes of systemic lupus erythematosus patients hospitalized due to infections vary among different ethnic populations. Thus, we determined the outcomes and associated factors in a group of Hispanics from Puerto Rico with systemic lupus erythematosus admitted due to severe infections. Records of systemic lupus erythematosus patients admitted to the Adult University Hospital, San Juan, Puerto Rico, from January 2006 to December 2014 were examined. Demographic parameters, lupus manifestations, comorbidities, pharmacologic treatments, inpatient complications, length of stay, readmissions, and mortality were determined. Patients with and without infections were compared using bivariate and multivariate analyses. A total of 204 admissions corresponding to 129 systemic lupus erythematosus patients were studied. The mean (standard deviation) age was 34.7 (11.6) years; 90% were women. The main causes for admission were lupus flare (45.1%), infection (44.0%), and initial presentation of systemic lupus erythematosus (6.4%). The most common infections were complicated urinary tract infections (47.0%) and soft tissue infections (42.0%). In t...Continue Reading

References

Dec 1, 1987·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·D TaterP Youinou
Jan 1, 1974·Arthritis and Rheumatism·P J StaplesR S Gordon
Aug 1, 1983·The Journal of Clinical Endocrinology and Metabolism·S V ShahS D Eilen
Jan 1, 1997·Diabetic Medicine : a Journal of the British Diabetic Association·M DelamaireB Genetet
May 26, 2001·Diabetes Care·A G BertoniF L Brancati
Jul 2, 2003·Journal of Clinical Pathology·C C Mok, C S Lau
Jul 17, 2009·Arthritis Research & Therapy·Guillermo Ruiz-IrastorzaCiriaco Aguirre

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