Clinical correlates of DSM-5 mixed features in bipolar disorder: A meta-analysis.

Journal of Affective Disorders
Francesco BartoliGiuseppe Carrà

Abstract

Systematic data on clinical correlates of mixed features in bipolar disorder are not available, so far. We conducted a systematic review and meta-analysis estimating the association between DSM-5 mixed features and candidate characteristics in depressive and manic/hypomanic episodes. We included observational studies indexed in the main electronic databases. The association between DSM-5 mixed features and relevant correlates was estimated using odds ratio (OR) and standardized mean difference (SMD) with 95% confidence intervals (CIs), for categorical and continuous variables, respectively. Analyses were based on random effects models. Eight studies were included, involving 3070 individuals (1495 with a major depressive episode and 1575 with hypo/manic episode). No clinical characteristics were associated with mixed features in subjects with a depressive episode. Among subjects with a manic/hypomanic episode, those with mixed features were more likely to have a history of suicide attempts (OR: 2.37; 95%CI: 1.42 to 3.94; I2=39.7%), co-occurring anxiety disorders (OR: 2.67; 95%CI: 1.28 to 5.57; I2=0%), and a rapid cycling course (OR=4.23; 95%CI: 1.29 to 13.81; I2=0%), with less severe manic symptoms (SMD=-0.40; 95%CI: -0.65 to -0...Continue Reading

References

Jul 23, 2009·BMJ : British Medical Journal·David MoherUNKNOWN PRISMA Group
Oct 9, 2009·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Alan C SwannGerard F Moeller
Jul 20, 2010·Bipolar Disorders·Frederick Cassidy
Apr 9, 2013·Journal of Affective Disorders·Eduard Vieta, Marc Valentí
Apr 23, 2013·Acta Psychiatrica Scandinavica·A Koukopoulos, G Sani
Jun 6, 2013·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Darrel A RegierDavid J Kupfer
May 27, 2014·Journal of Affective Disorders·Mauricio TohenHideaki Katagiri
Jul 9, 2014·The Journal of Clinical Psychiatry·André F CarvalhoKonstantinos N Fountoulakis
Jul 22, 2014·Journal of Affective Disorders·Mauricio TohenHideaki Katagiri
Dec 3, 2014·Journal of Affective Disorders·In Hee ShimWon-Myong Bahk
Apr 2, 2015·The Journal of Clinical Psychiatry·Giulio PerugiUNKNOWN BRIDGE-II-Mix Study Group
May 7, 2015·The Australian and New Zealand Journal of Psychiatry·María ReinaresEduard Vieta
May 23, 2015·Neuropsychiatric Disease and Treatment·Allan H Young, Jonas Eberhard
Jun 16, 2015·Acta Psychiatrica Scandinavica·G PerugiUNKNOWN the BRIDGE-II-Mix Study Group
Sep 16, 2015·CNS Drugs·Andrea FagioliniAllan H Young
Sep 14, 2016·CNS Spectrums·Joshua D Rosenblat, Roger S McIntyre
Dec 30, 2016·CNS Spectrums·Eva SoléEduard Vieta
Jan 14, 2017·Journal of Psychiatric Research·Francesco BartoliGiuseppe Carrà
Apr 16, 2017·Journal of Affective Disorders·Mauricio TohenMelvin G McInnis
Jul 26, 2017·Acta Psychiatrica Scandinavica·N VerdoliniUNKNOWN BRIDGE-II-Mix Study Group
Sep 13, 2017·Bipolar Disorders·Katharine A Smith, Andrea Cipriani
Sep 20, 2017·Journal of Affective Disorders·Gustavo H VázquezRoss J Baldessarini
Oct 11, 2017·The Journal of Clinical Psychiatry·Rakesh JainRoger S McIntyre
Jan 9, 2018·Journal of Affective Disorders·Lorenzo MazzariniUNKNOWN BRIDGE-II-Mix Study Group
Jun 5, 2018·Acta Psychiatrica Scandinavica·L TondoR J Baldessarini
May 24, 2019·Neuroscience and Biobehavioral Reviews·Francesco BartoliGiuseppe Carrà
Jul 16, 2019·Journal of Affective Disorders·Valentina CaricasoleBernardo Dell'Osso
Jul 26, 2019·Journal of Affective Disorders·Roger S McIntyreMehul Patel
Nov 23, 2019·Progress in Neuro-psychopharmacology & Biological Psychiatry·Gianna SepedeMassimo Di Giannantonio
Feb 6, 2020·The Psychiatric Clinics of North America·Isabella PacchiarottiNorma Verdolini

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.

© 2021 Meta ULC. All rights reserved