Clinical course and complications of infective endocarditis in patients growing up with congenital heart disease

International Journal of Cardiology
Walter KnirschPeter E Lange

Abstract

Although a high number of patients with congenital heart disease (CHD) undergo surgical palliation or definite correction up to adolescence, adult congenital heart disease (ACHD) may remain a potential lifelong risk factor for infective endocarditis (IE) in patients growing up with congenital heart disease (GUCH). In a retrospective case study of a tertiary care center long-term clinical course and complications of patients with IE and GUCH were analysed. Data of 52 patients with CHD, who fulfilled the Saiman criteria for infective endocarditis and were treated between April 1986 and March 2001, were identified: Risk factors for infective endocarditis were previous cardiovascular operation (51.9%), use of foreign material (38.5%), dental or other surgical procedures without recommended antibiotic prophylaxis (25.0%), or cardiac catheterization (5.8%). Staphylococcal (38.9%) or streptococcal species (35.2%) were cultivated in most cases as causative microorganisms. Complications were: recurrence of IE (7.7%), septic embolisms (30.8%) leading to central nervous complications (7.7%), embolism of pulmonary arteries (7.7%), renal arteries (1.9%), arteries of the extremities (9.6%), or infarction of spleen (1.9%). Other cardiac (23.1...Continue Reading

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Related Concepts

Dental Prophylaxis
Bacterial Endocarditis
Congenital Heart Defects
Cardiac Surgery Procedures
Retrospective Studies
Bacteremia
Gram-Negative Bacterial Infections
Gram-Positive Bacterial Infections
Oral Surgical Procedures

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