Clinical Course and Prognostic Factors of Acquired Third, Fourth, and Sixth Cranial Nerve Palsy in Korean Patients

Korean Journal of Ophthalmology : KJO
Kiyoung KimKyung Hyun Jin

Abstract

This study aimed to evaluate the clinical course and prognostic factors of acquired third, fourth, and sixth cranial nerve (CN) palsy grouped according to etiology. This study involved a retrospective review of the medical records of 153 patients who were diagnosed with acquired paralytic strabismus from January 2004 to July 2015. Outcomes, recovery rates, and time to recovery were investigated according to the affected CN: CN3, CN4, and CN6 palsies. The patients were classified into four groups based on etiology: idiopathic, traumatic, neoplastic, and vascular. The mean age of the patients was 59.8 ± 14.5 years and the mean follow-up period was 10.8 months. Out of the 153 patients, 63 (41.2%) had CN3 palsy, 35 (22.9%) had CN4 palsy, and 55 (35.9%) had CN6 palsy. The most common causes were vascular related (54.9%), followed by idiopathic (28.1%), trauma (8.5%), and neoplasm (5.88%). About 50% of the patients recovered within six months. Among the four etiologic groups, the idiopathic group showed the best prognosis because about 50% of the patients in this group recovered within three months. This was followed by the vascular, traumatic, and neoplastic groups. Cox proportional hazard analysis revealed a significant association...Continue Reading

References

May 25, 1992·American Journal of Ophthalmology·B W RichardsB R Younge
Jul 1, 1990·Neurology·H C Hopf, L Gutmann
Jan 1, 1970·Brain : a Journal of Neurology·A K AsburyC M Fisher
Jan 1, 1981·Archives of Ophthalmology·J A Rush, B R Younge
Jul 1, 1994·Archives of Ophthalmology·D M JacobsonP M Layde
Jul 4, 2002·American Journal of Ophthalmology·Scott K SandersValerie A Purvin
May 10, 2005·Ophthalmology·Sanjay V PatelJames P Burke
Aug 22, 2006·Indian Journal of Ophthalmology·Jean-Claude MwanzaDavid L Kayembe
Oct 2, 2007·Arquivos brasileiros de oftalmologia·Gustavo Bueno de CamargoCarlos Ramos de Souza-Dias
Jul 20, 2010·Journal of Neurosurgery·Alejandro Fernández CoelloJuan José Acebes Martín
Apr 24, 2013·Journal of the Chinese Medical Association : JCMA·Tsai-Hsuan HoSheu-Jiuan Sheu

❮ Previous
Next ❯

Citations

Jan 27, 2020·Acta neurologica Belgica·Francesco PagliaAntonio Santoro
Oct 17, 2020·Clinical & Experimental Ophthalmology·Binbin ZhuJianhua Yan
Dec 12, 2020·Heliyon·Tokunori KanazawaMasayuki Ishihara
May 8, 2021·Curēus·Steven DouediMary Sedarous

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of the Chinese Medical Association : JCMA
Tsai-Hsuan HoSheu-Jiuan Sheu
Transactions - Pennsylvania Academy of Ophthalmology and Otolaryngology
J S Kennerdell
© 2022 Meta ULC. All rights reserved