Clinical death and the measurement of stressed vascular volume

Critical Care Medicine
S Magder, B De Varennes

Abstract

To measure stressed vascular volume in humans and to review the concepts of stressed and unstressed vascular volume. Observational study during surgical procedure. Operating room at a university hospital. Five patients undergoing hypothermic circulatory arrest for surgery on major vessels. We measured the volume that drained from the patient to the reservoir of the pump when the pump was turned off. Stressed volume was 20.2+/-1.0 mL/kg, which is 30% of the predicted blood volume of these patients. The amount of blood volume that determines vascular filling pressure is only about a quarter of the total predicted volume, which means that there is a large reserve of unstressed volume that can be recruited to maintain vascular filling pressure.

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Citations

Apr 25, 2009·Der Anaesthesist·U Janssens, J Graf
Nov 5, 1999·Critical Care Medicine·A Boba
Dec 1, 2000·Critical Care Medicine·A H Morris
Feb 25, 2009·Critical Care Medicine·Shahar Bar-Yosef
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Oct 31, 2012·Critical Care : the Official Journal of the Critical Care Forum·Sheldon Magder
Jun 15, 2010·Critical Care : the Official Journal of the Critical Care Forum·Moritz Wyler von BallmoosStephan M Jakob
Dec 15, 2010·Critical Care : the Official Journal of the Critical Care Forum·William R HendersonA William Sheel
Dec 18, 2013·American Journal of Respiratory and Critical Care Medicine·Sheldon Magder
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Aug 29, 2012·Critical Care Medicine·Romain PersichiniXavier Monnet
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Sep 9, 2015·Current Opinion in Critical Care·Sheldon Magder
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