Clinical digital neuropathology: experience and observations from a departmental digital pathology training programme, validation and deployment.

Journal of Clinical Pathology
Bethany J WilliamsDarren Treanor

Abstract

To train and individually validate the neuropathologists in digital primary diagnosis and frozen section reporting using a novel protocol endorsed by the Royal College of Pathologists. The protocol allows early exposure to live digital reporting in a risk mitigated environment. Two specialist neuropathologists completed training in the use of a digital microscopy system for primary neuropathological diagnosis and frozen section assessment. Participants were exposed to training sets of 20 histology cases and 10 frozen sections designed to help them identify their personal digital diagnostic pitfalls. Following this, the pathologists viewed 340 live, complete neuropathology cases. All primary diagnoses were made on digital slides with immediate glass slide reconciliation before final case sign-out. There was 100% clinical concordance between the digital slide and glass slide assessment of frozen section cases for each pathologist, and these assessments corresponded with the ground truth diagnoses obtained from examination of definitive histology. For primary diagnosis, there was complete clinical concordance between digital slide and glass slide diagnosis in 98.1% of cases. The majority of discordances were related to grading dif...Continue Reading

References

May 3, 2013·Archives of Pathology & Laboratory Medicine·Liron PantanowitzUNKNOWN College of American Pathologists Pathology and Laboratory Quality Center
Nov 12, 2014·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Michael A ArnoldThomas Barr
Jul 12, 2016·Archives of Pathology & Laboratory Medicine·Edward GoacherDarren Treanor
May 4, 2017·Archives of Pathology & Laboratory Medicine·Bethany J WilliamsDarren Treanor
Aug 7, 2017·Journal of Clinical Pathology·Bethany Jill WilliamsDarren Treanor
Jun 10, 2019·Journal of Clinical Pathology·Bethany Jill WilliamsDarren Treanor

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Citations

May 26, 2021·Journal of Clinical Pathology·Tahir S Pillay
Jul 17, 2021·Journal of Pathology Informatics·Veena RamaswamySowmya B Uthaiah
Mar 14, 2021·Virchows Archiv : an International Journal of Pathology·Anna Luíza Damaceno AraújoPablo Agustin Vargas

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