Clinical effects of air pollution on the central nervous system; a review

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Robin M BabadjouniWilliam J Mack

Abstract

The purpose of this review is to describe recent clinical and epidemiological studies examining the adverse effects of urban air pollution on the central nervous system (CNS). Air pollution and particulate matter (PM) are associated with neuroinflammation and reactive oxygen species (ROS). These processes affect multiple CNS pathways. The conceptual framework of this review focuses on adverse effects of air pollution with respect to neurocognition, white matter disease, stroke, and carotid artery disease. Both children and older individuals exposed to air pollution exhibit signs of cognitive dysfunction. However, evidence on middle-aged cohorts is lacking. White matter injury secondary to air pollution exposure is a putative mechanism for neurocognitive decline. Air pollution is associated with exacerbations of neurodegenerative conditions such as Alzheimer's and Parkinson's diseases. Increases in stroke incidences and mortalities are seen in the setting of air pollution exposure and CNS pathology is robust. Large populations living in highly polluted environments are at risk. This review aims to outline current knowledge of air pollution exposure effects on neurological health.

Citations

Dec 14, 2018·Current Opinion in Psychiatry·Tom C RussMartie van Tongeren
Feb 6, 2019·Pediatric Pulmonology·Trinidad SánchezPablo E Brockmann
May 13, 2018·Environmental Health : a Global Access Science Source·Julián Alfredo Fernández-NiñoVíctor Alfonso Florez-Garcia
Feb 29, 2020·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Jody MorganAlison L Jones
May 16, 2020·Proceedings of the National Academy of Sciences of the United States of America·Dag AlnæsLars T Westlye
Sep 2, 2020·Environmental Science and Pollution Research International·Rubén D Arias-PérezJuan C Hernandez
Apr 23, 2019·Journal of Alzheimer's Disease : JAD·Maurizio ManigrassoPasquale Avino
Dec 19, 2019·Environmental Science and Pollution Research International·Hamzeh Mirshekari JahangiriGholamreza Goudarzi
Aug 21, 2020·Environmental Science and Pollution Research International·Ashif IqubalSyed Ehtaishamul Haque
Oct 5, 2019·Cardiovascular Research·Mark R Miller, David E Newby
Aug 11, 2018·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R MazzucchelliA Gil de Miguel
Aug 21, 2019·International Journal of Environmental Research and Public Health·Claudia Iveth Astudillo-GarcíaJulián Alfredo Fernández-Niño
Apr 11, 2018·Oxidative Medicine and Cellular Longevity·Nicholas E BuglakEdward S M Bahnson
Jan 31, 2020·Environmental Science and Pollution Research International·Hafiz Muhammad Abubakar Siddique, Adiqa K Kiani
Oct 17, 2020·The Science of the Total Environment·Maayan Yitshak-SadeAntonella Zanobetti
Oct 4, 2020·Annals of Epidemiology·Edwin van WijngaardenPhilip K Hopke
Feb 6, 2021·Reviews on Environmental Health·Mahwish AliSamina Akbar
Mar 15, 2020·Schizophrenia Research·Michelle A WorthingtonDonald C Goff
Apr 4, 2021·Antioxidants·Eduardo Felipe Alves Fernandes, Dennis Özcelik
May 1, 2021·Antioxidants·Maryse VanderplanckMagali Proffit
Jul 13, 2021·Frontiers in Cellular Neuroscience·Monika Jankowska-KieltykaIrena Nalepa

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