Clinical efficacy of florfenicol in the treatment of calf respiratory tract infections

The Veterinary Quarterly
V AslanM Corlu

Abstract

This paper reports on a study of the aetiology of calf pneumonia and the clinical efficacy of florfenicol, a new antibiotic in Turkey. Twenty-seven weaned and unweaned calves (13 males and 14 females) between 1 and 16 months of age brought to the clinics of Selçuk University, Faculty of Veterinary Science. Broncho-alveolar lavage (BAL) fluid samples were taken from the animals diagnosed to have upper respiratory tract infection associated with bronchitis (N=2), bronchitis (N=5), bronchopneumonia (N=4), pneumonia (N=3), pleuropneumonia (N=11), bronchopneumonia plus pulmonary oedema (N=2) based on the results of the clinical and laboratory examinations. Then microbiological isolation and antibiotic culturing were performed. The animals were treated with 1 ml/15 kg (20 mg/kg) florfenicol (Nuflor, DIF) twice within 48 hours via intramuscular injection. At the end of the treatment, 23 of the weaned and unweaned calves were completely healed, 1 calf had died and 3 calves showed no healing. The results of BAL samples and microbiological examinations of the 3 calves that did not respond to the treatment indicated that these cases were affected by mixed infections of yeasts, fungi, and bacteria. Widespread pleuropneumonia was observed. ...Continue Reading

References

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Citations

Nov 14, 2006·Applied and Environmental Microbiology·Ashish A SawantBhushan M Jayarao
Apr 17, 2009·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Glen C WeiserAlton C S Ward
Feb 15, 2011·Immunological Investigations·Guan ShuangDeng Xuming
Sep 22, 2009·International Immunopharmacology·Xuemei ZhangXuming Deng
May 20, 2008·International Immunopharmacology·Xuemei ZhangXuming Deng
Nov 17, 2010·Fundamental & Clinical Pharmacology·Xuemei ZhangXuming Deng
Dec 18, 2013·Journal of Veterinary Pharmacology and Therapeutics·P SidhuP Lees
Mar 14, 2013·The Veterinary Record·J IllambasP Lees

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