Oct 13, 2006

Clinical efficacy of probiotics: review of the evidence with focus on children

Journal of Pediatric Gastroenterology and Nutrition
Sonia MichailRobert Issenman

Abstract

Probiotics are marketed in several countries and widely used by pediatric health care providers. Although probiotics can be helpful for specific disorders, they have been broadly prescribed for disorders without clear evidence to support their use. Furthermore, in certain specific conditions, probiotics cause clinical deterioration. This report is a review and evaluation of the evidence or lack thereof to support a beneficial effect of probiotic agents in a variety of pediatric conditions and to review the safety and potential adverse events that may be encountered when using probiotics. It is also important to emphasize that probiotics are highly heterogeneous with differences in composition, biological activity, and dose among the different probiotic preparations.

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Citations

Mentioned in this Paper

Urinary Tract Infection
Irritable Bowel Syndrome
Adverse Event
Developmental Disabilities
Pouchitis
Inflammatory Bowel Diseases
Otitis Media
Dysentery
Allergic Reaction
Digestive System Disorders

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