Clinical evaluation of autologous platelet-rich fibrin in the treatment of multiple adjacent gingival recession defects: a 12-month study

The International Journal of Periodontics & Restorative Dentistry
Mustafa TunalιErhan Firatli

Abstract

Leukocyte- and platelet-rich fibrin (L-PRF) belongs to a new generation of platelet concentrates. There are limited numbers of studies focused on the use of L-PRF in gingival recession defects. This study evaluated the safety and effectiveness of using L-PRF membranes as a substitute for free connective tissue grafts (CTGs) as a treatment method for gingival recession defects. A total of 44 Miller Class I/II gingival recessions that were bilateral, adjacent, and greater than 3 mm in size were selected. Each recession site was randomly assigned to the test group (L-PRF) or the control group (CTG). After 12 months, root coverage was 76.63% and 77.36% in the L-PRF and CTG groups, respectively. It is suggested that L-PRF membrane may be an alternative graft material for treating multiple adjacent recessions greater than 3 mm in size without a requirement for additional surgery.

Associated Clinical Trials

Citations

Mar 5, 2015·Journal of Oral Biology and Craniofacial Research·Sujata MohantyJitender Dabas
Aug 20, 2016·Acta Odontologica Scandinavica·Gülbahar UstaoğluMustafa Tunali
Oct 3, 2018·The Cochrane Database of Systematic Reviews·Leandro ChambroneGiovan Paolo Pini Prato
Jul 31, 2019·Journal of Periodontology·Leandro ChambroneGiovan Paolo Pini Prato
Sep 29, 2019·Journal of Investigative and Clinical Dentistry·Arada PatarapongsantiPathawee Khongkhunthian
Jun 28, 2020·Clinical Oral Investigations·Richard J MironAnton Sculean
Apr 3, 2020·Journal of Applied Oral Science : Revista FOB·Serap Karakış Akcan, Berrin Ünsal
May 30, 2017·Clinical Oral Investigations·Richard J MironJoseph Choukroun
Nov 13, 2015·Journal of Periodontology·Vittorio Moraschini, Eliane Dos Santos Porto Barboza
May 18, 2019·Medicina·Alexandru Florian GrecuMarius Eugen Ciurea

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