PMID: 6986899Jan 1, 1980Paper

Clinical evaluation of clobetasone butyrate: a comparative study of its effects in postoperative inflammation and on intraocular pressure

The British Journal of Ophthalmology
T G RamsellS R Walker

Abstract

Clobetasone butyrate, a new corticosteroid with a high topical activity, has been compared with prednisolone phosphate and a placebo in the treatment of inflammation following cataract extraction. These 2 steroids were more effective in relieving postoperative inflammation than placebo (P less than 0.05), though no obvious clinical differences between the 2 compounds emerged from this investigation. However, a single-blind comparative study against betamethasone phosphate in patients suspected of having steroid-induced glaucoma showed that, while betamethasone phosphate significantly raised intraocular pressure, clobetasone butyrate had only a minimal effect, and this difference was statistically significant (P less than 0.02).

Citations

Oct 1, 1981·The British Journal of Ophthalmology·K R WilhelmusN S Rice
Mar 1, 1983·The British Journal of Ophthalmology·S C Debnath, A B Richards
May 3, 2000·International Ophthalmology Clinics·E M Dodds
Sep 1, 1981·The British Journal of Ophthalmology·D Lloyd-JonesP G Watson
Jun 1, 1981·The British Journal of Ophthalmology·C A CarterS R Walker
Dec 9, 2003·Sports Biomechanics·Morteza Shahbazi-Moghaddam
Jul 17, 1998·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·O M OriowoB E Robinson
Mar 1, 1991·Journal of Cataract and Refractive Surgery·L W GrossmanR W Faaland
Dec 12, 2012·European Journal of Ophthalmology·Pasquale AragonaDomenico Puzzolo

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