PMID: 11334201May 4, 2001Paper

Clinical evaluation of nine hollow-fibre membrane oxygenators

Perfusion
P A SegersS Eilander

Abstract

In a comparative study we investigated the performance characteristics of nine hollow-fibre oxygenators. In a clinical setting, 10 units of each type of oxygenator were tested for oxygen exchange, transoxygenator pressure drop, heat exchanger performance and blood trauma. The oxygenators included are Maxima PRF Plus, Affinity, Forte, Affinity NT, Quantum, Optima, Capiox 1.8, Hilite and Quadrox. Ninety patients scheduled for elective coronary bypass surgery were enrolled in the study. Cardiotomy suction blood was not allowed to mix with the circulating blood. Samples were taken preoperatively (t1), immediately after cooling and crossclamping of the aorta (t2), during rewarming (t3), and postoperatively (t4). The results showed that under clinical conditions all of the tested oxygenators are well capable of meeting the normal and above-normal oxygen needs. The Quantum and Affinity NT are the best performing oxygenators with respect to oxygen transfer. The Quantum oxygenator with a small membrane surface area of 1.9 m2 has also the highest oxygen transfer per square metre. A direct relationship between shunt fraction and blood flow could not be established in all oxygenators. The lowest shunt fraction at 4 litres blood flow was se...Continue Reading

Citations

Dec 12, 2003·The Annals of Thoracic Surgery·William S Haworth
Apr 28, 2010·Artificial Organs·Antoine P SimonsJos G Maessen
Mar 27, 2015·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Luigi CastagnaNicolò Patroniti
Apr 22, 2015·Medical Engineering & Physics·Filippo ConsoloAlberto Redaelli
Sep 27, 2015·Perfusion·Roger D P Stanzel, Mark Henderson
Jan 10, 2008·Perfusion·H DunninghamA Vuylsteke
Feb 24, 2018·Artificial Organs·Rik H J HendrixPatrick W Weerwind
Oct 3, 2019·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Alexander WahbaUNKNOWN EACTS/EACTA/EBCP Committee Reviewers
Oct 13, 2006·The International Journal of Artificial Organs·D P QueirozM N de Pinho
Mar 3, 2005·The International Journal of Artificial Organs·B MeynsD Vlasselaers
Feb 27, 2013·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Cindy S BarrettRavi R Thiagarajan

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