Clinical evaluation of the iterative metal artifact reduction algorithm for CT simulation in radiotherapy

Medical Physics
Marian AxenteDimitre Hristov

Abstract

To clinically evaluate an iterative metal artifact reduction (IMAR) algorithm prototype in the radiation oncology clinic setting by testing for accuracy in CT number retrieval, relative dosimetric changes in regions affected by artifacts, and improvements in anatomical and shape conspicuity of corrected images. A phantom with known material inserts was scanned in the presence/absence of metal with different configurations of placement and sizes. The relative change in CT numbers from the reference data (CT with no metal) was analyzed. The CT studies were also used for dosimetric tests where dose distributions from both photon and proton beams were calculated. Dose differences and gamma analysis were calculated to quantify the relative changes between doses calculated on the different CT studies. Data from eight patients (all different treatment sites) were also used to quantify the differences between dose distributions before and after correction with IMAR, with no reference standard. A ranking experiment was also conducted to analyze the relative confidence of physicians delineating anatomy in the near vicinity of the metal implants. IMAR corrected images proved to accurately retrieve CT numbers in the phantom study, independ...Continue Reading

References

Jan 1, 1996·Physics in Medicine and Biology·U SchneiderA Lomax
Jul 21, 2009·Medical Physics·Wen C HsiAndries N Schreuder
Nov 26, 2010·Medical Physics·Esther MeyerMarc Kachelriess
Apr 10, 2012·Medical Physics·Esther MeyerMarc Kachelrieß
Apr 19, 2012·Physics in Medicine and Biology·Joost M Verburg, Joao Seco
Oct 9, 2012·Medical Physics·Seemeen KarimiHarry Martz
Jan 16, 2013·Journal of Applied Clinical Medical Physics·Maria F SpadeaJoao Seco
Feb 1, 2013·Physics in Medicine and Biology·Mu-Han LinC-M Ma
Apr 6, 2013·Medical Physics·Yanbo ZhangXuanqin Mou
May 31, 2013·Medical Physics·C Glide-HurstI J Chetty
Jul 5, 2013·Medical Physics·Joost M Verburg, Joao Seco
Apr 23, 2014·International Journal of Radiation Oncology, Biology, Physics·Moti Raj PaudelSatyapal Rathee

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Citations

Apr 3, 2016·Medical Physics·Mehrsima AbdoliHabib Zaidi
Apr 6, 2017·Australasian Physical & Engineering Sciences in Medicine·Connor GuilfoileMichael House
Mar 13, 2018·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Masaki KatsuraOsamu Abe
Mar 13, 2016·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Manuel MaerzBarbara Dobler
Oct 24, 2019·The British Journal of Radiology·Ole MartinBenedikt M Schaarschmidt
Sep 10, 2015·Physics in Medicine and Biology·Paolo FaraceMarco Cianchetti
Jun 9, 2020·Journal of Applied Clinical Medical Physics·Daniela BrancoDavid Followill
Oct 12, 2019·Australasian Physical & Engineering Sciences in Medicine·P LimJ Sykes
May 17, 2017·Journal of X-ray Science and Technology·Mehran Yazdi, Zohre Mansourian
Jan 29, 2019·Ophthalmic Plastic and Reconstructive Surgery·Keirnan L WillettJohn H Woo
Jan 19, 2021·Journal of X-ray Science and Technology·Hui TangXu Dong Bao
Jun 26, 2018·Radiologic Clinics of North America·Bhavik N Patel, Daniele Marin
May 4, 2021·Journal of Applied Clinical Medical Physics·Sathyathas PuvanasunthararajahSaskia M Camps
May 10, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Jean-Luc DumasLudovic De Marzi
May 27, 2021·Biomedical Physics & Engineering Express·Li ZhaoIndra J Das
May 29, 2021·International Journal of Radiation Oncology, Biology, Physics·Robert W MutterShannon M MacDonald
Jul 20, 2021·Journal of Clinical Orthopaedics and Trauma·Siddhartha SharmaDhillon Mandeep
Aug 19, 2021·Dento Maxillo Facial Radiology·Nicole V HinchyMina Mahdian

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