PMID: 6979317May 1, 1982Paper

Clinical evaluation of the relative effectiveness of multidose crystalloid and cold blood potassium cardioplegia in coronary artery bypass graft surgery: a nonrandomized matched-pair analysis

The Annals of Thoracic Surgery
A J RobertsL L Michaelis

Abstract

Controversy exists concerning the most effective method of myocardial protection during coronary artery bypass graft operations. Accordingly, we performed a matched-pair analysis between 25 patients receiving multidose hypothermic potassium crystalloid cardioplegia and 25 other patients receiving cold blood potassium cardioplegia. Patients were matched on the basis of preoperative ejection fraction (EF) and the number of anatomically similar stenotic coronary arteries. The adequacy of myocardial protection was assessed by serial perioperative determinations of radionuclide ventriculography, hemodynamic measurements, analyses of electrocardiograms and serum levels of MB-CK. We found that the level of myocardial protection was similar between unstratified groups. However, when subgroups were selected on the basis of prolonged aortic cross-clamp time (greater than ninety minutes) or impaired preoperative left ventricular function (EF less than 40%), there was a suggestion that cold blood cardioplegia may be advantageous.

References

Oct 1, 1979·Annals of Surgery·F D LoopW L Proudfit
Dec 1, 1979·The American Journal of Cardiology·D H TyrasV L Willman
Nov 1, 1978·The American Journal of Cardiology·G M LawrieD W Chapman
Aug 1, 1979·The American Journal of Cardiology·F D LoopA D Pichard
Oct 1, 1979·The Annals of Thoracic Surgery·C J HiltonM T McEnany
Mar 1, 1978·Circulation·H D McIntosh, J A Garcia
Jul 19, 1979·The New England Journal of Medicine·J W KirklinE H Blackstone
Dec 1, 1979·Circulation·J W KirklinA Oberman
Oct 1, 1977·The Annals of Thoracic Surgery·G D Buckberg
May 1, 1976·The Journal of Surgical Research·G D WilliamsJ K Callaway
Oct 6, 1975·The American Journal of Cardiology·R S Ross
Mar 1, 1980·The Annals of Thoracic Surgery·H B BarnerV L Willman
Jan 1, 1981·The Annals of Thoracic Surgery·H R BaurF L Gobel
Jul 2, 1955·Lancet·D G MELROSEJ B BAKER

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Citations

Feb 13, 2003·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Kazutomo MinamiReiner Körfer
Mar 1, 1992·The Annals of Thoracic Surgery·P NatafI Gandjbakhch
Sep 1, 1986·The Annals of Thoracic Surgery·J Vinten-JohansenA R Cordell
Jun 1, 1986·The Annals of Thoracic Surgery·W A SievertsenA J Roberts
Jul 1, 1984·The Journal of Surgical Research·A J RobertsJ A Alexander
Mar 1, 1987·The Journal of Surgical Research·K G WarnerS F Khuri
Aug 1, 1986·The Annals of Thoracic Surgery·F OgumaS Eguchi
Dec 1, 1991·The Annals of Thoracic Surgery·H B Barner
Jun 1, 1983·The Annals of Thoracic Surgery·G F Tyers
Jun 24, 2004·Asian Cardiovascular & Thoracic Annals·Alexander A AlbertJürgen Ennker
Dec 7, 2019·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Farid GojayevYasemin Canillioglu
May 1, 1987·Progress in Cardiovascular Diseases·N A Silverman, S Levitsky

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