PMID: 15368688Sep 17, 2004Paper

Clinical evaluation of transrectal power doppler imaging in the detection of prostate cancer

International Urology and Nephrology
Masahiko InaharaHaruo Ito

Abstract

To evaluate the clinical usefulness of power Doppler imaging (PDI), we compared this method to gray-scale transrectal ultrasound (TRUS) in the detection of prostate cancer. A total of 101 men with abnormally high serum prostate specific antigen (PSA) levels and/or abnormal digital rectal examination (DRE) findings were assessed using TRUS and PDI. Random systematic sextant and bilateral far lateral prostate biopsies were performed in all cases. In addition, when TRUS revealed a hypoechoic lesion or PDI revealed a hypervascular lesion (HVL), these lesions were directly biopsied. Of the 101 patients, 48 (47.5%), 42 (41.5%) and 42 (41.5%) were suspicious of having prostate cancer by DRE, TRUS and PDI, respectively. Prostate needle biopsy revealed prostate cancer in 39 patients (38.6%) and benign prostatic diseases in 62 patients (61.4%). If prostate needle biopsy was avoided when PDI was negative, then PDI eliminated the need for biopsy in 59 of the 101 patients (rate of biopsy procedures saved: 58.4%) and missed only 8 (13.6%) prostate cancers. Moreover, in 63 patients with intermediate PSA (3-10 ng/ml), the rate of biopsy procedures saved by DRE, TRUS, and PDI was 60.3%, 65.1%, and 68.3%, respectively, and the rate of cancers mi...Continue Reading

Citations

May 8, 2007·Ultrasound in Medicine & Biology·Mehdi MoradiPurang Abolmaesumi
Aug 3, 2006·International Journal of Urology : Official Journal of the Japanese Urological Association·Tomonori KatoTomohiko Ichikawa
Nov 6, 2009·BJU International·Michael L EisenbergKatsuto Shinohara
Feb 27, 2015·IEEE Transactions on Bio-medical Engineering·Farhad ImaniPurang Abolmaesumi
May 3, 2015·IEEE Transactions on Medical Imaging·Farhad ImaniParvin Mousavi
Jul 23, 2005·The Urologic Clinics of North America·Fatih AtugRaju Thomas
Jun 27, 2007·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Ahmet Tuncay TurgutVikram Dogra

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