Abstract
To review clinical experience and studies with anti-EGFR therapies in metastatic CRC, SCCHN, and NSCLC. Case studies in each tumor type will also be outlined. Research articles and patient case histories. Several phase II/III trials have shown the activity of anti-EGFR therapy in CRC, SCCHN, and NSCLC. Treatment confers substantial clinical benefit with improved symptoms, particularly in previously treated patients. Toxicity of anti-EGFR therapies is generally manageable and non-overlapping with other treatment options, including chemotherapy and radiotherapy. It is important for nurses to further advance our understanding of anti-EGFR therapies and continue to encourage patient enrollment in ongoing trials of anti-EGFR therapy.
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