Clinical experience with anti-EGFR therapy

Seminars in Oncology Nursing
Anne Fish-SteagallRebecca Sipples

Abstract

To review clinical experience and studies with anti-EGFR therapies in metastatic CRC, SCCHN, and NSCLC. Case studies in each tumor type will also be outlined. Research articles and patient case histories. Several phase II/III trials have shown the activity of anti-EGFR therapy in CRC, SCCHN, and NSCLC. Treatment confers substantial clinical benefit with improved symptoms, particularly in previously treated patients. Toxicity of anti-EGFR therapies is generally manageable and non-overlapping with other treatment options, including chemotherapy and radiotherapy. It is important for nurses to further advance our understanding of anti-EGFR therapies and continue to encourage patient enrollment in ongoing trials of anti-EGFR therapy.

References

May 15, 2001·Endocrine-related Cancer·J Mendelsohn
Mar 20, 2003·Seminars in Oncology·Patricia M Lorusso
May 16, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Masahiro FukuokaJosé Baselga
Mar 3, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Giuseppe GiacconeDavid H Johnson
Mar 3, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Roy S HerbstDavid H Johnson
Mar 3, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Leonard B SaltzRobert J Mayer
May 4, 2004·The Lancet Oncology·Marion Harris
May 15, 2004·International Journal of Radiation Oncology, Biology, Physics·Roy S Herbst
Jul 23, 2004·The New England Journal of Medicine·David CunninghamEric Van Cutsem
Jan 29, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ki Young ChungLeonard B Saltz

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Citations

Jan 26, 2008·Seminars in Oncology Nursing·Susan Moore
Sep 27, 2016·Clinical Journal of Oncology Nursing·Martin WallnerHanna Mayer
Mar 18, 2008·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Pamela H Carney, Cathy L Ollom
Apr 10, 2009·The Oncologist·Nathan A Pennell, Thomas J Lynch

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