Apr 1, 1985

Clinical experience with the use of charcoal haemoperfusion: is prostacyclin required?

Life Support Systems : the Journal of the European Society for Artificial Organs
H J KennedyD R Triger

Abstract

Twenty patients have undergone a total of 47 charcoal haemoperfusions without the use of prostacyclin. A fall in platelet numbers and evidence of platelet activation have been found during haemoperfusion but few clinical complications have been observed. Therefore, we believe that the clinical value of the addition of prostacyclin during charcoal haemoperfusion has not been proven. Nevertheless, its apparent protective effect on platelet numbers and activation indicates that further controlled trials of the use of prostacyclin during charcoal haemoperfusion are required.

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Mentioned in this Paper

Corophyllin
Flolan
Drug-Induced Acute Liver Injury
Poisoning
Charcoal
Epoprostenol
Platelet Activation
Monospan
Narcotan
Platelet Count Measurement

About this Paper

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