Clinical experiences in the Gambro-preservation unit: analysis of 101 human cadaver kidneys

European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
G HorpácsyG May

Abstract

101 human cadaver kidneys were preserved by means of hypothermic pulsatile perfusion in the Gambro perfusion unit with human albumin as perfusate. Perfusate flow and some biochemical parameters were assessed during perfusion and correlated with renal function after transplantation. There is a good correlation between perfusate flow and recovery of physiological renal function. LDH released to the perfusate as viability test is of limited value: a direct correlation was only found between LDH activity and perfusion time, and LDH activity and ischemia time. Determination of pH and lactic acid level 1 h after beginning of perfusion is without practical value according to our experience. The quality of albumin in perfusion solution influences the immediate graft function.

References

Apr 26, 2013·Artificial Organs·Marcel C DirkesThomas M van Gulik
Feb 8, 2020·Transplant International : Official Journal of the European Society for Organ Transplantation·Francesco GuzziJames P Hunter
Jan 1, 1980·Scandinavian Journal of Urology and Nephrology·P R OlsenS Larsen

Related Concepts

Ischemia
Kidney Function Tests
ALB
Perfusion
Albumin Human, USP
Graft Survival
Kidney
Lactates
Cadaver
Both Kidneys

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