DOI: 10.1101/474114Nov 19, 2018Paper

Clinical experiences with the use of oxytocin injection by healthcare providers in a South-Western State Nigeria: A Cross sectional study.

BioRxiv : the Preprint Server for Biology
Chioma Stella R. EjekamJude Nwokike


Background: Post-Partum Hemorrhage (PPH), is a leading cause of maternal mortality in Nigeria and most low and middle income countries(LMIC). The World Health Organization(WHO) strongly recommends oxytocin as effective, affordable and the safest drug of first choice in the prevention and treatment of PPH in the third stage of labor. However, there are concerns about its quality. Very high prevalence of poor-quality oxytocin, especially in Africa and Asia has been reported in literature. Excessive and inappropriate use is also common with oxytocin in low-resource settings. Objective: To assess clinical experiences with quality of oxytocin used by healthcare providers in Lagos State Nigeria. Methods: It was a descriptive cross-sectional study done in 2017. Seven hundred and five respondents (doctors and nurses) who use oxytocin for obstetrics and gynaecological services were recruited from 195 health facilities (public and registered private) across Lagos State. Data collection was quantitative, using a pretested self-administered questionnaire. Data analysis was done using IBM SPSS version 21. Statistical significance was set at 5%( p<0.05). Ethical approval was obtained from Lagos University Teaching Hospital Health Research Et...Continue Reading

Related Concepts

Cross-Sectional Studies
Pharmaceutical Preparations
Postpartum Hemorrhage
Computer Software
World Health Organization
Prophylactic Treatment

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