Clinical Feasibility of Monitoring Resting Heart Rate Using a Wearable Activity Tracker in Patients With Thyrotoxicosis: Prospective Longitudinal Observational Study

JMIR MHealth and UHealth
Jie Eun LeeJae Hoon Moon

Abstract

Symptoms and signs of thyrotoxicosis are nonspecific and assessing its clinical status is difficult with conventional physical examinations and history taking. Increased heart rate (HR) is one of the easiest signs to quantify this, and current wearable devices can monitor HR. We assessed the association between thyroid function and resting HR measured by a wearable activity tracker (WD-rHR) and evaluated the clinical feasibility of using this method in patients with thyrotoxicosis. Thirty patients with thyrotoxicosis and 10 controls were included in the study. Participants were instructed to use the wearable activity tracker during the study period so that activity and HR data could be collected. The primary study outcomes were verification of changes in WD-rHR during thyrotoxicosis treatment and associations between WD-rHR and thyroid function. Linear and logistic model generalized estimating equation analyses were performed and the results were compared to conventionally obtained resting HR during clinic visits (on-site resting HR) and the Hyperthyroidism Symptom Scale. WD-rHR was higher in thyrotoxic patients than in the control groups and decreased in association with improvement of thyrotoxicosis. A one standard deviation-...Continue Reading

References

Jan 1, 1980·Acta Haematologica·Y KurataT Kitani
Sep 3, 2002·QJM : Monthly Journal of the Association of Physicians·R Malik, H Hodgson
Jan 6, 2005·Endocrine Reviews·George J Kahaly, Wolfgang H Dillmann
Apr 6, 2005·Clinical Endocrinology·Jan G den HollanderArie Berghout
Oct 10, 2007·Circulation·Irwin Klein, Sara Danzi
Apr 16, 2010·The Journal of Clinical Endocrinology and Metabolism·K BoelaertJ A Franklyn
Oct 4, 2011·Indian Journal of Endocrinology and Metabolism·Sanjay KalraAakshit Goyal
Mar 27, 2012·The Medical Clinics of North America·Leonidas H Duntas, Gabriela Brenta
Apr 4, 2012·Indian Journal of Endocrinology and Metabolism·Gopal Basu, Anjali Mohapatra
Oct 9, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Esther N Klein HesselinkJoop D Lefrandt
Apr 29, 2014·Emergency Medicine Clinics of North America·Danielle Devereaux, Semhar Z Tewelde
Aug 12, 2015·European Journal of Internal Medicine·Angelos KyriacouAkheel A Syed
Oct 13, 2016·JAMA Cardiology·Robert WangMarc Gillinov
Dec 22, 2016·Thyroid : Official Journal of the American Thyroid Association·Ye An KimBo Youn Cho
Aug 26, 2017·Cell·Ali TorkamaniEric J Topol
Mar 29, 2018·Endocrinology and Metabolism·Jie Eun LeeJae Hoon Moon

❮ Previous
Next ❯

Citations

Sep 5, 2020·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·Eva SteinbergerWinfried März
Jul 2, 2019·Endocrinology and Metabolism·Jae Hoon Moon, Steven R Steinhubl
Oct 11, 2020·The Journal of Clinical Endocrinology and Metabolism·Aaron B Neinstein, Umesh Masharani
Feb 25, 2021·The Journal of Clinical Endocrinology and Metabolism·Norlela SukorNor Azmi Kamaruddin
Mar 25, 2021·Endocrinology and Metabolism·Meelim Kim, Hyung Jin Choi

❮ Previous
Next ❯

Clinical Trials Mentioned

NCT03009357

Software Mentioned

R
own
rHR
Fitbit
SPSS Statistics
iOS
WD

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.