Clinical features and management of parastomal pyoderma gangrenosum in inflammatory bowel disease

Digestion
Motoi UchinoNaohiro Tomita

Abstract

Pyoderma gangrenosum (PG) is often associated with inflammatory bowel disease even after bowel surgery, but it remains an extremely rare pathology. The purpose of this study was to investigate the clinical features and treatment of PG and to consider proper management for peristomal PG. Demographic data for patients who underwent colorectal surgery with ostomy creation at Hyogo College of Medicine between July 2007 and July 2011 were prospectively collected. The main outcome measures were postoperative occurrence of peristomal PG by type: explosive and rapidly spreading type (type R) and indolent and gradually spreading type (type G). Overall prevalence was 11/738 (1.5%), with type R in 5 patients and type G in 6. Type R and type G were significantly more common in ulcerative colitis and Crohn's disease, respectively (p = 0.01). Type R developed within 6 days after surgery. Type G developed a mean of 52 days after surgery. Complete healing required a long time in both types, with means of 69 days for type R and 48 days for type G. Although peristomal PG was a rare complication after surgery, differences in the development of PG were observed between ulcerative colitis and Crohn's disease. Careful observation and knowledge of PG...Continue Reading

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Citations

Apr 25, 2014·Gastroenterology Report·Xian-Rui Wu, Bo Shen
Jan 1, 2016·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jianfeng GongJieshou Li
Aug 13, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Ayal HirschDavid T Rubin
Jun 23, 2015·Gastroenterología y hepatología·Raúl Vicente Olmedo MartínMiguel Jiménez Pérez
Jan 26, 2018·Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Società Italiana Di Dermatologia E Sifilografia·Maddalena NapolitanoNicola Balato
Jul 13, 2019·International Wound Journal·Wendy A PearsonKeryln J Carville
May 23, 2020·The Journal of Dermatology·Nobuyuki Kikuchi, Toshiyuki Yamamoto
May 4, 2018·Inflammatory Bowel Diseases·Xinying Wang, Bo Shen
Dec 9, 2020·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·Carlos Cerdán SantacruzJavier Cerdán Miguel
Feb 6, 2021·Enfermería clínica·Leticia Julve-HerraizBlai García-Costa
Mar 11, 2021·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·Gabriele RoveronUNKNOWN Multidisciplinary Italian Study Group for STOmas (MISSTO)

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