Clinical features and natural history of occupational asthma due to western red cedar (Thuja plicata)

The American Journal of Medicine
M Chan-YeungS Koener

Abstract

After an average follow-up interval of three and a half years (range one to nine years), 125 patients with occupational asthma due to red cedar exposure were re-examined. Fifty patients remained in the same job. All of them continued to have asthmatic attacks requiring regular medication for relief of symptoms. They had worse lung function and ther bronchial reactivity to methacholine increased. Seventy-five patients left the industry; half of them became asymptomatic, whereas the remaining half continued to have recurrent attacks of asthma. Several factors were of prognostic significance. Those with a shorter duration of exposure as well as a shorter duration of symptoms prior to diagnosis and removal from exposure showed improvement. Those who remained symptomatic tended to be older; they had longer duration of exposure and a longer duration of symptoms prior to diagnosis. They tended to have more abnormal results of lung function studied and more marked bronchial hyper-reactivity to methacholine at the time of diagnosis. They also tended to have dual asthmatic reaction rather than late asthmatic reaction to inhalation challenge with red cedar extract. Smoking, race and degree of peripheral blood eosinophilia did not play a r...Continue Reading

Citations

Jun 30, 1994·The Science of the Total Environment·G Pisati, S Zedda
Jul 1, 1982·The Journal of Allergy and Clinical Immunology·M Chan-Yeung
Jul 1, 1984·The Journal of Allergy and Clinical Immunology·S R DurhamA B Kay
Jan 1, 1985·The Journal of Allergy and Clinical Immunology·H NordmanM Tuppurainen
Jan 1, 1988·The Journal of Allergy and Clinical Immunology·D W Cockcroft
Mar 6, 1998·Disease-a-month : DM·D A Schwartz, M W Peterson
Nov 1, 1991·Respiratory Medicine·C E Bucknall
Oct 31, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Jung-Won ParkChein-Soo Hong
Oct 30, 2003·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Luisa RicciardiStefania Isola
Apr 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·E Ihre, O Zetterström
Aug 1, 1989·Thorax·D J Hendrick
Oct 1, 1988·British Journal of Industrial Medicine·K M VenablesA J Newman Taylor
Feb 1, 1987·British Journal of Industrial Medicine·K M Venables
Apr 1, 1985·Thorax·D J Hendrick
Apr 1, 1985·Thorax·M Yeung, S Grzybowski
Jun 1, 1993·British Journal of Industrial Medicine·P F GannonP S Burge
Jan 1, 1993·British Journal of Industrial Medicine·G PisatiS Zedda
Nov 1, 1996·Occupational and Environmental Medicine·F J LinM Chan-Yeung
Apr 8, 1999·Thorax·A J Frew
May 16, 2000·Occupational and Environmental Medicine·A B BohadanaP Goutet
Aug 10, 2000·Environmental Health Perspectives·L J Lombardo, J R Balmes
Jan 31, 2002·Mediators of Inflammation·A Custovic, A Woodcock
May 20, 2004·Occupational and Environmental Medicine·V SchlünssenT Sigsgaard
Apr 20, 2005·Occupational and Environmental Medicine·P J NicholsonC Boyle
Jul 9, 2005·Environmental Health Perspectives·Judith Green-McKenzie, Debra Hudes
Oct 20, 2005·Occupational and Environmental Medicine·D M WildA D Paltiel
Nov 13, 2008·Archivos de bronconeumología·Xavier CasasJosep Morera
Jul 1, 1990·Respiratory Medicine·S R Durham
Jun 1, 1990·The Journal of Allergy and Clinical Immunology·F E HargreaveM T Newhouse
Apr 13, 1999·The Journal of Allergy and Clinical Immunology·C E Reed
Mar 1, 1989·The Journal of Allergy and Clinical Immunology·G H AyarsE Y Chi
Dec 8, 2004·Immunology and Allergy Clinics of North America·Paul G Vigo, Mitchell H Grayson
Jan 1, 1987·British Journal of Industrial Medicine·A CarossoM Bugiani

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