Clinical features and outcome in North American adults with moyamoya phenomenon

Stroke; a Journal of Cerebral Circulation
Christopher L HallemeierColin P Derdeyn

Abstract

To describe baseline clinical features and outcomes of adults with moyamoya phenomenon treated at a single North American institution. We identified 34 adults with moyamoya phenomenon by review of angiographic records. Clinical presentation and baseline stroke risk factors were obtained by chart review. Follow-up was obtained prospectively. A 5-year Kaplan-Meier stroke risk was calculated. The median age was 42 (range 20 to 79) years. Twenty-five were women. The initial symptom was ischemia, hemorrhage, or asymptomatic in 24, 7, and 3 patients, respectively. Twenty-two had bilateral involvement and 12 had unilateral moyamoya vessels. Baseline stroke risk factors were similar between groups. The median follow-up in 31 living patients was 5.1 (range 0.2 to 19.6) years. Fourteen patients were treated with surgical revascularization (20 total hemispheres). In medically treated symptomatic hemispheres, the 5-year risk of recurrent ipsilateral stroke was 65% after the initial symptom and 27% after angiographic diagnosis. Patients with bilateral involvement presenting with ischemic symptoms were at the highest risk of subsequent stroke (n=17, 5-year risk of stroke with medical treatment after first symptom of 82%). In surgically treat...Continue Reading

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References

Dec 31, 1997·Clinical Neurology and Neurosurgery·S J Peerless
Oct 3, 1998·JAMA : the Journal of the American Medical Association·R L GrubbW J Powers
Aug 31, 2001·Archives of Neurology·E Y YilmazJ Biller
Jan 18, 2003·Lancet·P M RothwellUNKNOWN Carotid Endarterectomy Trialists' Collaboration
Jan 13, 2005·Cerebrovascular Diseases·Peter HornMichael Hennerici
Sep 24, 2005·Stroke; a Journal of Cerebral Circulation·Satoshi KurodaYoshinobu Iwasaki
Sep 28, 2005·Neurology·Ken UchinoDavid L Tirschwell

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Citations

Dec 25, 2009·Journal of Neurology·Joanne R FestaRonald M Lazar
Dec 29, 2009·Journal of Neurology·Markus Kraemer, Peter Berlit
Jul 3, 2009·The New England Journal of Medicine·Colin P Derdeyn
Mar 20, 2009·The New England Journal of Medicine·R Michael Scott, Edward R Smith
Feb 11, 2010·Applied Neuropsychology·Lauren R SchwarzLindsay A Levine
Jul 21, 2011·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M KraemerN Khan
Jan 1, 2010·BMJ Case Reports·Yoshinori Matsuoka, Makoto Hashizume
May 18, 2011·Pediatric Neurosurgery·Kentaro HayashiIzumi Nagata
Mar 16, 2012·Neurosurgery·Robert M StarkeAaron S Dumont
Jan 17, 2012·Internal Medicine·Makiko TanakaKazuo Kitagawa
Oct 5, 2010·Neurologia Medico-chirurgica·Jun C Takahashi, Susumu Miyamoto
Apr 2, 2009·Neurosurgical Focus·Robert M StarkeE Sander Connolly
Apr 2, 2009·Neurosurgical Focus·Gordon M BurkeBernard R Bendok
May 26, 2009·Journal of Neurosurgery·Raphael GuzmanGary K Steinberg
Jun 3, 2010·Journal of Neurosurgery. Pediatrics·Arata WatanabeHiroyuki Kinouchi
Dec 3, 2010·Journal of Neurosurgery. Pediatrics·Paritosh PandeyGary K Steinberg
Jun 3, 2011·Neurosurgical Focus·David G WeinbergBernard R Bendok
Mar 14, 2008·Neurosurgical Focus·William W AshleyFady T Charbel
Jan 10, 2014·Neurosurgery·Eric J AriasGregory J Zipfel
Jan 11, 2014·Journal of Neurosurgery·Ning LinR Michael Scott
Feb 7, 2014·Acta neurochirurgica·Kentaro HayashiIzumi Nagata
Feb 18, 2014·Journal of Neurosurgery. Pediatrics·Eric M JacksonEdward R Smith
Apr 15, 2014·Journal of Neurosurgery·Huai-Yu TongXin-Guang Yu
Mar 22, 2014·AJNR. American Journal of Neuroradiology·M K StrotherM J Donahue
Apr 4, 2014·Neurosurgical Review·Bradley A GrossKai U Frerichs
Oct 4, 2014·Journal of Neurosurgery·Pankaj K AgarwallaChristopher S Ogilvy
Oct 7, 2010·Journal of Neurosurgical Anesthesiology·Tariq ParraySaif Siddiqui
Sep 20, 2007·Cerebrovascular Diseases·J ParkI S Hamm
Oct 31, 2012·Acta neurochirurgica·Bradley A Gross, Rose Du
Jun 26, 2008·The International Journal of Neuroscience·Filiz KocZafer Koc
Jun 13, 2015·Brain Injury : [BI]·Hidetoshi MatsukawaOsamu Takahashi
Oct 17, 2015·British Journal of Neurosurgery·Pennylouise HeverChristos Tolias

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