Clinical Features and Outcomes of Repeated Endoscopic Therapy for Esophagogastric Variceal Hemorrhage in Cirrhotic Patients: Ten-Year Real-World Analysis

Gastroenterology Research and Practice
Jia-Li MaHong-Shan Wei

Abstract

This study is aimed at evaluating the survival of cirrhotic patients with different etiologies after endoscopic therapy for acute variceal bleeding and the effect of repeated endotherapy on patients' prognosis. We retrospectively evaluated the clinical features and outcomes between cirrhotic patients with chronic HBV or HCV infections and other etiologies. The 3-year and 5-year survival rates and rehemorrhage rate in one year between the viral and nonviral cirrhosis patients were compared by Kaplan-Meier curves and log-rank test. Cox analysis was used to identify the impact factors that affect the long-term survival of patients with cirrhosis and variceal bleeding after endotherapy. Out of 2665 patients with liver cirrhosis and variceal hemorrhage selected from our medical center between September 2008 and December 2017, a total of 1342 patients were included for analysis. The median follow-up duration was 32.9 months (range 0.16-111.4 months), the 3- and 5-year cumulative survival rates were 75.3% and 52.8%, respectively. The median survival time was significantly longer in viral cirrhosis patients (47.1 months [95% CI: 24.9-69.1]) compared with nonviral cirrhosis patients (37.0 months [95% CI: 25.0-56.0], p = 0.001). The 3-ye...Continue Reading

References

Sep 1, 1985·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D WestabyR Williams
Apr 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M GreeveT L Wright
Sep 26, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A PoonawalaP J Thuluvath
Aug 27, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Gennaro D'AmicoUNKNOWN Cooperative Study Group
May 5, 2006·Seminars in Liver Disease·Chia-Ming Chu, Yun-Fan Liaw
Aug 31, 2007·The American Journal of Gastroenterology·Guadalupe Garcia-TsaoUNKNOWN Practice Parameters Committee of American College of Gastroenterology
Feb 27, 2010·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Peter JepsenHendrik Vilstrup
Nov 10, 2010·Liver International : Official Journal of the International Association for the Study of the Liver·Annarosa FloreaniVincenzo Baldo
Mar 23, 2012·Journal of Hepatology·UNKNOWN European Association For The Study Of The Liver
Apr 17, 2012·Journal of Hepatology·Cheng-Yuan PengYun-Fan Liaw
Nov 23, 2013·Journal of Korean Medical Science·Ki Soo KangJeong Kee Seo
Jan 18, 2014·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Vipul JairathAndrew Burroughs
Aug 19, 2014·Clinical Endoscopy·Young Dae Kim
Jan 30, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jeong Won JangKwang-Hyub Han
Apr 19, 2015·Gut·Dhiraj TripathiUNKNOWN Clinical Services and Standards Committee of the British Society of Gastroenterology
Sep 15, 2015·Lancet·Elizabeth J CareyKeith D Lindor
Feb 19, 2016·Journal of Clinical Gastroenterology·Badr Al-BawardyLouis M Wong Kee Song
Mar 8, 2016·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Hourin ChoNaomi Uemura
May 18, 2016·Scandinavian Journal of Gastroenterology·Perttu SahlmanMartti Färkkilä
Aug 12, 2016·Liver International : Official Journal of the International Association for the Study of the Liver·Setor K Kunutsor
May 24, 2017·Gastroenterology Report·Ihteshamul Haq, Dhiraj Tripathi
Nov 8, 2017·Hepatology International·Gin-Ho Lo
Feb 27, 2018·Gastroenterology·Mostafa IbrahimJacques Devière

❮ Previous
Next ❯

Citations

Mar 1, 2021·Annals of Hepatology·Ling-Ling HeHong-Shan Wei
Jul 13, 2021·The Journal of International Medical Research·Yao-Chang LuoFei-Fei Xuan

❮ Previous
Next ❯

Software Mentioned

SPSS
BAVENO VI
GraphPad Prism

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva
A Albillos Martínez
Journal of Gastroenterology and Hepatology
P Calés
© 2022 Meta ULC. All rights reserved