Clinical features and prognostic factors in papillary thyroid microcarcinoma depends on age.

Journal of the Korean Surgical Society
Jin-Kyu ChoSang-Kyung Choi

Abstract

Clinical outcomes of papillary thyroid microcarcinoma (PTMC) vary. In general, age at diagnosis is an independent prognostic factor in conventional papillary thyroid carcinoma. However, it is unclear in patients of PTMC. The purpose of this study was to identify clinicopathologic features and prognostic factors of PTMC according to patients' age. Five hundred twenty-seven patients who received thyroid surgery and diagnosed as having PTC between January 2001 and December 2009 were included. The clinical data were retrospectively analyzed. We divided the patients into two groups; group I who were younger than 45 years, and group II who were 45 years old or older. The mean tumor size and incidences of neck lymph nodes involvement of group I was larger than group II. In group II, however, there were more patients who had multiple cancer foci and were body mass index ≥ 25 kg/m(2). The overall incidence of recurrent disease was 3.2%. The incidence of recurrence was higher in group II (2.0% vs. 4.0%), without a statistical difference. In multivariate analysis, the significant risk factors of recurrence were male gender and multifocality in group I, and lymph node metastasis and multifocality in group II. In particular, the male gender...Continue Reading

References

Dec 1, 1992·British Journal of Cancer·M T GoodmanL R Wilkens
Dec 1, 1996·The British Journal of Surgery·M D Bramley, B J Harrison
Jun 14, 2003·Thyroid : Official Journal of the American Thyroid Association·Yasuhiro ItoAkira Miyauchi
Nov 4, 2004·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·E OrsenigoV Di Carlo
Apr 13, 2005·Acta Oto-laryngologica·Miaw-Jene LiouChuen Hsueh
Aug 10, 2006·Endocrine Journal·Junho LeeSung-Kil Lim
Feb 12, 2008·World Journal of Surgery·Shiro NoguchiShin Watanabe
Jan 7, 2009·Current Opinion in Oncology·Simon Grodski, Leigh Delbridge
Apr 8, 2009·Thyroid : Official Journal of the American Thyroid Association·Giuseppe MercanteVerter Barbieri
Apr 8, 2009·Thyroid : Official Journal of the American Thyroid Association·Nimmi AroraThomas J Fahey
Dec 19, 2009·World Journal of Surgery·Yasuhiro ItoAkihiro Miya
Feb 25, 2010·Annals of Surgical Oncology·Stephen B Edge, Carolyn C Compton
May 27, 2010·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·D GiordanoT Ferri
Jun 4, 2010·The Journal of Clinical Endocrinology and Metabolism·John E PaesMatthew D Ringel

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Citations

Jul 3, 2015·Experimental and Therapeutic Medicine·Wei ZhengGuizhi Zhang
Mar 20, 2015·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Altay AliyevEren Berber
May 3, 2014·Pathology Oncology Research : POR·Fábio Muradás GirardiCláudio Galleano Zettler
Aug 1, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·L ZhangX Li
Oct 30, 2016·The Lancet. Diabetes & Endocrinology·Sophie LeboulleuxMartin Schlumberger
Mar 14, 2013·The Journal of Clinical Endocrinology and Metabolism·Pasqualino MalandrinoRiccardo Vigneri
Oct 13, 2019·World Journal of Surgery·Dessislava I StefanovaToni Beninato
Mar 20, 2021·Archives of Endocrinology and Metabolism·Fernanda Nascimento FaroCarolina Ferraz

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