Clinical features and prognostic factors of listeriosis: the MONALISA national prospective cohort study

The Lancet Infectious Diseases
Caroline CharlierMONALISA study group

Abstract

Listeriosis is a severe foodborne infection and a notifiable disease in France. We did a nationwide prospective study to characterise its clinical features and prognostic factors. MONALISA was a national prospective observational cohort study. We enrolled eligible cases declared to the National Reference Center for Listeria (all microbiologically proven) between Nov 3, 2009, and July 31, 2013, in the context of mandatory reporting. The outcomes were analysis of clinical features, characterisation of Listeria isolates, and determination of predictors of 3-month mortality or persisting impairment using logistic regression. A hierarchical clustering on principal components was also done for neurological and bacteraemic cases. The study is registered at ClinicalTrials.gov, number NCT01520597. We enrolled 818 cases from 372 centres, including 107 maternal-neonatal infections, 427 cases of bacteraemia, and 252 cases of neurolisteriosis. Only five (5%) of 107 pregnant women had an uneventful outcome. 26 (24%) of 107 mothers experienced fetal loss, but never after 29 weeks of gestation or beyond 2 days of admission to hospital. Neurolisteriosis presented as meningoencephalitis in 212 (84%) of 252 patients; brainstem involvement was onl...Continue Reading

Citations

Apr 19, 2017·The Journal of Infection·Merel M KoopmansArie van der Ende
Nov 28, 2017·Nature Reviews. Microbiology·Lilliana Radoshevich, Pascale Cossart
Jun 15, 2017·British Journal of Hospital Medicine
Nov 28, 2017·Current Opinion in Infectious Diseases·Matthijs C Brouwer, Diederik van de Beek
Jul 7, 2018·The Journal of Biological Chemistry·Moeko Toride KingCory L Brooks
Sep 5, 2018·PLoS Genetics·Mariela ScorttiJose Vazquez-Boland
Sep 1, 2018·Journal of Neuropathology and Experimental Neurology·Joo-Yeon Engelen-LeeDiederik van de Beek
Jan 5, 2018·BMJ Case Reports·Hanna Bjarkhamar PoulsenShahin Gaini
Jan 31, 2019·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Nicolas Weiss, Dominique Thabut
Jul 5, 2019·The Medical Journal of Australia·Caitlin L KeighleyGwendolyn L Gilbert
Sep 17, 2019·Journal of Medical Microbiology·Maria X Cardenas-AlvarezTeresa M Bergholz
Jun 24, 2017·Emerging Infectious Diseases·Alexandra MouraMarc Lecuit
May 21, 2019·The Pediatric Infectious Disease Journal·Nadja Hawwa VissingUlrikka Nygaard
Nov 22, 2019·Infectious Diseases·Sanne De SmetSarah Loof
Oct 22, 2019·International Reviews of Immunology·Gamal AllamAdel Abdel-Moneim
Mar 19, 2020·Cellular Microbiology·Marc Lecuit
Aug 30, 2019·Current Opinion in Ophthalmology·Jeffrey Gluckstein, Sashank Prasad
May 26, 2017·Archives of Gynecology and Obstetrics·Mitko MadjunkovShinya Ito
Jun 6, 2018·Frontiers in Cellular and Infection Microbiology·Hélène BierneMounia Kortebi
Aug 23, 2018·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Ivo Van WalleUNKNOWN European Listeria WGS typing group
Jan 20, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Caroline CharlierMarc Lecuit
Jan 16, 2020·Intensive Care Medicine·Geert MeyfroidtRomain Sonneville
May 5, 2020·Virulence·Caroline CharlierMarc Lecuit
Dec 15, 2017·Expert Review of Anti-infective Therapy·Lisa PucciGiuseppina Liuzzi
Nov 6, 2018·Internal Medicine Journal·Nicholas Young, Mark Thomas
Jun 20, 2019·Obstetrical & Gynecological Survey·Amanda M CraigJennifer L Thompson
Feb 14, 2020·The New England Journal of Medicine·Juno ThomasLucille H Blumberg
May 5, 2020·Virulence·Caroline Charlier, Marc Lecuit

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