Clinical features and radiological characteristics of pulmonary cryptococcosis

The Journal of International Medical Research
Hui DengXinying Xue

Abstract

Objective Diagnosis of pulmonary cryptococcosis is difficult. In this study, we examined the clinical and radiological features that increase the diagnostic accuracy for pulmonary cryptococcosis. Methods This retrospective study included clinical data from 68 patients with pulmonary cryptococcosis from 2012 to 2016 in 3 tertiary hospitals. Results Among the 68 patients, 39 (57.35%) had no complications, 39 (57.35%) had clinical symptoms, 6 (8.82%) had a history of occupational exposure, 27 (39.71%) had a single nodule/mass (the most common type of pulmonary cryptococcosis) on chest computed tomography images, 21 (30.88%) had multiple nodules/masses, 16 (23.53%) had ground glass opacity with or without nodules, 2 (2.94%) had miliary nodules, and 2 (2.94%) had enlarged mediastinal lymph nodes. Fifty-three (77.94%) patients had lesions with irregular margins, 33 (48.53%) had spiculated lesions, 32 (47.06%) had air bronchograms, 9 (13.24%) had cavities, and 4 (5.88%) had calcifications. Twenty-four patients underwent surgery, 35 received antifungal treatment, and 9 received both treatments. Conclusion The clinical features and computed tomography signs found in this study are not specific for a diagnosis of pulmonary cryptococcosis...Continue Reading

References

Jan 5, 2011·American Journal of Respiratory and Critical Care Medicine·Andrew H LimperUNKNOWN American Thoracic Society Fungal Working Group
Dec 21, 2012·Science Translational Medicine·Gordon D BrownTheodore C White
Jan 30, 2014·Revista Da Sociedade Brasileira De Medicina Tropical·Valter Luis Iost TeodoroMaria José Soares Mendes-Giannini
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Sep 24, 2015·Seminars in Respiratory and Critical Care Medicine·C C ChangS C-A Chen

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Citations

Jun 25, 2019·Journal of Bronchology & Interventional Pulmonology·Roberto Martin-DeleonCarles Agustí
Jun 13, 2020·The Journal of International Medical Research·Ming YangPeiyuan Xia
Jan 26, 2021·Journal of Medical Imaging and Radiation Oncology·Binglin JianXiaoli Ma

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Methods Mentioned

BETA
biopsy

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Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

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