Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area

JAMA : the Journal of the American Medical Association
Christopher M BoothAllan S Detsky

Abstract

Severe acute respiratory syndrome (SARS) is an emerging infectious disease that first manifested in humans in China in November 2002 and has subsequently spread worldwide. To describe the clinical characteristics and short-term outcomes of SARS in the first large group of patients in North America; to describe how these patients were treated and the variables associated with poor outcome. Retrospective case series involving 144 adult patients admitted to 10 academic and community hospitals in the greater Toronto, Ontario, area between March 7 and April 10, 2003, with a diagnosis of suspected or probable SARS. Patients were included if they had fever, a known exposure to SARS, and respiratory symptoms or infiltrates observed on chest radiograph. Patients were excluded if an alternative diagnosis was determined. Location of exposure to SARS; features of the history, physical examination, and laboratory tests at admission to the hospital; and 21-day outcomes such as death or intensive care unit (ICU) admission with or without mechanical ventilation. Of the 144 patients, 111 (77%) were exposed to SARS in the hospital setting. Features of the clinical examination most commonly found in these patients at admission were self-reported ...Continue Reading

Citations

Mar 18, 2004·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Narinder S PaulGordon L Weisbrod
Sep 4, 2009·Future Virology·Jason D Graci, Craig E Cameron
Sep 30, 2003·Southern Medical Journal·Fares J Khater, Jonathan P Moorman
Apr 12, 2006·PLoS Medicine·James V LawlerJason Paragas
Mar 15, 2014·Current Opinion in Pulmonary Medicine·David S HuiAlimuddin Zumla
Mar 3, 2004·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Takeshi FujiiAikichi Iwamoto
Dec 2, 2004·Proceedings of the National Academy of Sciences of the United States of America·Jenn-Han ChenYu-Ju Chen
Oct 3, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sandra R KnowlesLarissa Matukas
Jul 1, 2004·Proceedings of the National Academy of Sciences of the United States of America·Chung-Yi WuChi-Huey Wong
Apr 22, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kendall A MarcusJohn H Powers
Jul 18, 2014·Current Opinion in Infectious Diseases·Jaffar A Al-TawfiqZiad A Memish
Jul 23, 2014·Travel Medicine and Infectious Disease·Jaffar A Al-TawfiqZiad A Memish
Nov 23, 2013·Future Medicinal Chemistry·Adeyemi O Adedeji, Stefan G Sarafianos
Dec 31, 2004·Obstetrics and Gynecology·Mark H YudinKevin A Gough
Oct 21, 2003·QJM : Monthly Journal of the Association of Physicians·D A GronebergK F Chung
Oct 9, 2003·Emerging Infectious Diseases·Gang LiYihua Zhou
Nov 12, 2003·Emerging Infectious Diseases·Kamaljit SinghPaul A Tambyah
Nov 20, 2003·Critical Care : the Official Journal of the Critical Care Forum·Christopher M Booth, Thomas E Stewart
Dec 6, 2003·BMJ : British Medical Journal·Peter A SingerRandi Zlotnik Shaul
Jan 14, 2004·Emerging Infectious Diseases·Owen Tak-Yin TsangSik-To Lai
Mar 20, 2004·Emerging Infectious Diseases·Jiang WuAnne Schuchat
Mar 20, 2004·Emerging Infectious Diseases·Elmira T IsakbaevaUNKNOWN SARS Investigation Group
Mar 20, 2004·Emerging Infectious Diseases·Mark LoebStephen D Walter
Mar 20, 2004·Emerging Infectious Diseases·Michael D ChristianUNKNOWN SARS Investigation Team
Mar 20, 2004·Emerging Infectious Diseases·John A JerniganRita F Hefland
Mar 20, 2004·Emerging Infectious Diseases·Raymond S M Wong, David S Hui
Mar 20, 2004·Emerging Infectious Diseases·Kwok-Kwong LauKwok-Yuen Yuen
Mar 26, 2004·Emerging Infectious Diseases·Jairam R LingappaUmesh D Parashar
Mar 27, 2004·Emerging Infectious Diseases·Gee-Gwo YangLih-Shinn Wang
Apr 14, 2004·Emerging Infectious Diseases·Tony MazzulliKevin C Kain
Jun 18, 2004·Emerging Infectious Diseases·Mona R LoutfyGlenn Berall
Jun 18, 2004·Emerging Infectious Diseases·L Clifford McDonaldDaniel B Jernigan
Jun 18, 2004·Emerging Infectious Diseases·Jann-Tay WangPan-Chyr Yang
Jun 18, 2004·Emerging Infectious Diseases·Emily L C TanLawrence W Stanton
Jul 16, 2004·Postgraduate Medical Journal·D S C HuiP C Ng

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