Abstract
Pregnancy is a risk factor for progression of diabetic retinopathy (DR). Despite the common opinion about the regression of DR after childbirth, it is possible for the disease to progress aggressively, which can cause loss of visual functions when treated untimely. To present clinical cases with different course of development of DR in pregnant women with type 1 diabetes mellitus (DM1). Five pregnant women with DM1 lasting more than 8 years were examined. Glycemic level of all patients was higher than normal (glycated hemoglobin (HbA1c) of more than 6.1%). Ophthalmologic examination was carried out including fundus photography, optical coherence tomography (OCT) of the macular area, Angio-OCT. The most significant factors in the progression of DR in pregnant women are DR1 compensation, severity and stabilization of DR during the preconception period, presence of a concomitant pathology. Timely detection of signs of progression of DR and therapeutic measures taken during pregnancy, in particular laser coagulation, were shown to stabilize the course of the disease and prevent loss of vision in pregnant women with DM1. Clinical course of DR in pregnancy can vary between absence of manifestation, stabilization, and progression. Pro...Continue Reading
References
Apr 1, 1992·American Journal of Obstetrics and Gynecology·B RosennM J Lipman
Jan 1, 1990·Diabetes Care·B E KleinR Klein
Jan 1, 1988·Survey of Ophthalmology·J S Sunness
Jan 1, 1986·Acta Endocrinologica. Supplementum·L Serup
Dec 1, 1986·Archives of Ophthalmology·R L PhelpsN Freinkel
Nov 1, 1985·International Ophthalmology·G SoubraneG Coscas
Feb 1, 1980·The British Journal of Ophthalmology·B L HerculesJ Jeacock
Jan 1, 1984·British Journal of Obstetrics and Gynaecology·J H PriceJ M Harley
Jan 1, 1980·Metabolic and Pediatric Ophthalmology·L LaatikainenK O Raivio
Jul 1, 1995·Diabetes Care·A HemachandraT J Orchard
Jul 1, 1995·Diabetes·J E Tooke
Oct 1, 1994·Diabetes Research and Clinical Practice·Y OmoriM Sanaka
May 1, 1995·Diabetes Care·E Y ChewL B Holmes
Jan 1, 1996·Eye·S M RassamE M Kohner
Mar 1, 1997·The British Journal of Ophthalmology·R M Best, U Chakravarthy
Feb 10, 1998·Diabetic Medicine : a Journal of the British Diabetic Association·M Lövestam-AdrianE Agardh
Feb 21, 2004·Eye·W C ChanR M Best
Apr 9, 2008·Diabetologia·C S Arun, R Taylor
Mar 13, 2010·Diabetologia·K L RasmussenE R Mathiesen
Jun 12, 2010·Diabetic Medicine : a Journal of the British Diabetic Association·M VestgaardE R Mathiesen
Nov 18, 2010·Drugs·Taina K Mattila, Anthonius de Boer
May 31, 2011·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Hendrée E JonesKevin E O'Grady
Dec 21, 2012·Diabetic Medicine : a Journal of the British Diabetic Association·R HampshireP Dodson
May 7, 2015·Journal of Diabetes Research·Aoife M EganFidelma P Dunne
Nov 16, 2018·Journal of Nephrology·Donatella Spotti