Clinical features of hepatitis E virus infection in Ibaraki, Japan: autochthonous hepatitis E and acute-on-chronic liver failure

The Tohoku Journal of Experimental Medicine
Yuki InagakiNobuhiro Ohkohchi

Abstract

Hepatitis E caused by hepatitis E virus (HEV) is a serious public health concern in developing countries where HEV is mainly transmitted through contaminated water. Recently, in industrialized countries, autochthonous hepatitis E, a porcine zoonosis, has been increasingly recognized. In Japan, the number of national notifications of acute hepatitis E has increased since the introduction of anti-HEV IgA antibody measurement, covered by the national health insurance program, in 2011. In the past three years, we examined five patients of acute hepatitis or acute-on-chronic liver failure caused by HEV infection who presented various clinical courses in the southern area of Ibaraki prefecture in Japan. Of these patients, 78-year-old and 63-year-old male patients presented acute hepatitis E and recovered by only bed rest. The latter patient had a history of consuming grilled or undercooked pork and shellfish prior to the onset of hepatitis E. Among the five patients examined, the infection route was detected only in this patient. Of note, a 65-year-old female patient presented severe hepatitis associated with painless thyroiditis. The patient was diagnosed with probable autoimmune hepatitis and was successfully treated with prednisol...Continue Reading

References

Aug 31, 2002·Journal of Clinical Microbiology·Hitoshi MizuoHiroaki Okamoto
Nov 1, 2002·The New England Journal of Medicine·Kazuyuki SuzukiHiroaki Okamoto
Mar 20, 2003·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Sachiyo OhnishiShunji Mishiro
Aug 9, 2003·Lancet·Shuchin TeiShunji Mishiro
Dec 23, 2003·Internal Medicine·Hiroaki OkamotoTsutomu Nishizawa
Feb 12, 2004·Autoimmunity Reviews·Sandro Vento, Francesca Cainelli
Apr 20, 2004·Journal of Hepatology·Yoko TamadaHiromi Ishibashi
Aug 7, 2004·Journal of Clinical Microbiology·Yuko KoizumiHiroaki Okamoto
Feb 21, 2006·Emerging Infectious Diseases·Tian-Cheng LiTatsuo Miyamura
Sep 15, 2006·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Sachiyo OhnishiShunji Mishiro
Nov 28, 2006·Journal of Hepatology·Subrat Kumar AcharyaSubrat Kumar Panda
Mar 17, 2007·Virus Research·Hiroaki Okamoto
Jan 15, 2008·Journal of Hepatology·R H Purcell, S U Emerson
Mar 10, 2009·Liver International : Official Journal of the International Association for the Study of the Liver·Yellapu Radha KrishnaGour Choudhuri
Jul 19, 2011·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·René GerolamiPhilippe Colson
Apr 28, 2012·Gastroenterology·Heiner WedemeyerMichael P Manns
May 3, 2012·Lancet·Nassim KamarHarry R Dalton
Jul 25, 2012·Journal of Gastroenterology·Kayoko SugawaraSatoshi Mochida
Nov 23, 2012·Emerging Infectious Diseases·Claire CrossanLinda Scobie
Dec 13, 2012·Journal of Viral Hepatitis·L Scobie, H R Dalton
Jan 18, 2013·World Journal of Gastroenterology : WJG·Bin XuXin-Hui Guo
Apr 5, 2013·World Journal of Hepatology·Catarina Lima VieiraCarlos Cardoso
Jun 1, 2013·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Masaharu Takahashi, Hiroaki Okamoto
Oct 18, 2013·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
Jan 28, 2014·PloS One·Sven PischkeHeiner Wedemeyer
Feb 18, 2014·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Satoshi MochidaHirohito Tsubouchi

❮ Previous
Next ❯

Citations

May 25, 2016·Food Microbiology·João R MesquitaMaria S J Nascimento
Feb 14, 2017·Advances in Virology·Olusesan Adeyemi AdelabuAnthony Ifeanyi Okoh
Apr 27, 2018·Advances in Anatomic Pathology·Daniela Lenggenhager, Achim Weber
Nov 16, 2018·Liver International : Official Journal of the International Association for the Study of the Liver·Michael EderHarald Hofer
Mar 23, 2021·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Yukio OshiroShuji Suzuki

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Hepatitis

Autoimmune hepatitis formerly called lupoid hepatitis, is a chronic, autoimmune disease of the liver that occurs when the body's immune system attacks liver cells causing the liver to be inflamed. Discover the latest research on autoimmune hepatitis here.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Liver International : Official Journal of the International Association for the Study of the Liver
Stéphanie Haim-BoukobzaAnne-Marie Roque-Afonso
Gastroentérologie Clinique Et Biologique
Guillaume DeestYannick Bacq
Médecine et maladies infectieuses
Florence AbravanelJ Izopet
Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
Jeyamani, George Kurian
© 2021 Meta ULC. All rights reserved