Clinical features of idiopathic inflammatory polymyopathy in the Hungarian Vizsla

BMC Veterinary Research
Anna TauroClare Rusbridge

Abstract

A retrospective study of the clinicopathological features of presumed and confirmed cases of idiopathic inflammatory polymyopathy in the Hungarian Vizsla dog and guidelines for breeding. 369 medical records were reviewed (1992-2013) and 77 Hungarian Vizslas were identified with a case history consistent with idiopathic inflammatory polymyopathy. Inclusion criteria were: group 1 (confirmed diagnosis); histopathology and clinical findings compatible with an inflammatory polymyopathy and group 2 (probable diagnosis); clinical findings compatible with a polymyopathy including dysphagia, sialorrhea, temporal muscle atrophy, elevated serum creatine kinase (CK) activity, and sufficient clinical history to suggest that other neuromuscular disorders could be ruled out. Some group 2 dogs had muscle biopsy, which suggested muscle disease but did not reveal an inflammatory process. The mean age of onset was 2.4 years; male dogs were slightly overrepresented. Common presenting signs were dysphagia, sialorrhea, masticatory muscle atrophy, and regurgitation. Common muscle histopathological findings included degenerative and regenerative changes, with multifocal mononuclear cell infiltration with lymphoplasmacytic myositis of variable severity...Continue Reading

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Citations

Jul 18, 2018·The Journal of Small Animal Practice·A LorekR Dennis
May 19, 2021·The Journal of Small Animal Practice·H P HongG D Shelton
Aug 14, 2021·Journal of the American Veterinary Medical Association·Iñaki Prado-ChecaLdo Vet

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Methods Mentioned

BETA
urine stream
biopsy
biopsies

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