Clinical features of immune rejection after corneoscleral transplantation

American Journal of Ophthalmology
Weiyun ShiLixin Xie

Abstract

To summarize the clinical features of immune rejection after corneoscleral transplantation. A retrospective, noncomparative, observational case series. Patients who received corneoscleral transplantation because of whole corneal ulcer or corneal perforation at Shandong Eye Institute from July 1, 2003 through July 31, 2005 were included. Fourteen patients (14 eyes) with immune rejection but not recurrence or other complications were reviewed, including ocular vision, rejection onset time, symptoms, and characteristics. The average rejection time in the 14 eyes was 35 days. The rejection arose rapidly, and the mean best-corrected visual acuity decreased to counting fingers or hand movements. Circular limbal congestion and edema developed with circuitous and dilatational vessels. Whole graft edema and Descemet membrane folds were present, but no epithelial rejection line, endothelial rejection line, or keratic precipitate were observed. The average intraocular pressure (IOP) dropped from 13.6 mm Hg to 7.4 mm Hg. Seven eyes had shallow anterior chambers (AC). Retinal and choroidal edema was observed in five eyes. The clinical features of immune rejection after corneoscleral transplantation include rapid onset of rejection, vision d...Continue Reading

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Citations

Sep 4, 2012·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M-T EddyA Hassenstein
May 18, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Y TanV L Perez
Jun 28, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ting WangWeiyun Shi
Nov 15, 2018·Journal of Ophthalmology·Xiaolin QiHua Gao
Apr 4, 2021·Journal of Clinical Medicine·Karl Anders KnutssonPaolo Rama

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