PMID: 9661829Jul 14, 1998Paper

Clinical features of non-tuberculous mycobacterial disease: comparisons between smear-positive and smear-negative cases, and between Mycobacterium avium and Mycobacterium intracellulare

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
Y ObayashiJ Takahara

Abstract

To evaluate the differences in clinical symptoms and radiological findings between smear-positive non-tuberculous mycobacteria (NTM) and smear-negative, culture-positive NTM. Also, to evaluate the differences in clinical symptoms and radiological findings between Mycobacterium avium and M. intracellulare. A retrospective study was performed of 200 cases with positive pulmonary cultures for NTM between January 1989 and December 1996. It was determined whether or not pulmonary disease was caused by NTM using the 1990 criteria recommended by the American Thoracic Society. Clinical symptoms and radiological findings were compared between groups. Fever and hemoptysis were more frequently observed in smear-positive patients (26/50, 52%, and 24/50, 48%, respectively) than in smear-negative, culture-positive patients (8/38, 21.1%, P < 0.005, 8/38, 21.1%, P < 0.01, respectively). In addition, cavity formation was more frequently observed in chest computed tomography scans of smear-positive patients (19/36, 52.8%) than in smear-negative patients (6/31, 19.4%, P < 0.005). Finally, cavity formation tended to be more frequently observed with M. avium than with M. intracellulare. The present study demonstrates differences in clinical symptom...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
X Xia, X Gui
The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
M JankovicJ van Ingen
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
Hai-rong HuangYu Ma
© 2022 Meta ULC. All rights reserved