Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.

Chaolin HuangBin Cao


A recent cluster of pneumonia cases in Wuhan, China, was caused by a novel betacoronavirus, the 2019 novel coronavirus (2019-nCoV). We report the epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of these patients. All patients with suspected 2019-nCoV were admitted to a designated hospital in Wuhan. We prospectively collected and analysed data on patients with laboratory-confirmed 2019-nCoV infection by real-time RT-PCR and next-generation sequencing. Data were obtained with standardised data collection forms shared by WHO and the International Severe Acute Respiratory and Emerging Infection Consortium from electronic medical records. Researchers also directly communicated with patients or their families to ascertain epidemiological and symptom data. Outcomes were also compared between patients who had been admitted to the intensive care unit (ICU) and those who had not. By Jan 2, 2020, 41 admitted hospital patients had been identified as having laboratory-confirmed 2019-nCoV infection. Most of the infected patients were men (30 [73%] of 41); less than half had underlying diseases (13 [32%]), including diabetes (eight [20%]), hypertension (six [15%]), and cardiovascular...Continue Reading

Associated Clinical Trials

Apr 6, 2020·Efstratios Koutroumpakis
Apr 24, 2020·Philippe Jouvet
Apr 24, 2020·Prof. Dr. Kamal Mohammed Okasha


Jan 29, 2020·The New England Journal of Medicine·Lan T PhanQuang D Pham
Feb 1, 2020·The New England Journal of Medicine·Michelle L HolshueUNKNOWN Washington State 2019-nCoV Case Investigation Team
Feb 1, 2020·European Journal of Clinical Investigation·Matteo BassettiDaniele Roberto Giacobbe
Feb 6, 2020·The International Journal of Occupational and Environmental Medicine·Parham Habibzadeh, Emily K Stoneman
Feb 7, 2020·European Radiology·Yueying Pan, Hanxiong Guan
Jan 30, 2020·Journal of Medical Virology·Domenico BenvenutoMassimo Ciccozzi
Feb 11, 2020·International Health·Hong-Ying LiPeter Daszak
Feb 6, 2020·Journal of Medical Virology·Foster Kofi AyitteyAhmed Habib
Feb 7, 2020·Epidemiology and Health·Sukhyun RyuUNKNOWN Korean Society of Epidemiology 2019-nCoV Task Force Team
Feb 6, 2020·Journal of Medical Virology·Marta GiovanettiMassimo Ciccozzi
Feb 13, 2020·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Chantal B E M Reusken On Behalf Of Evd-LabNet And Erli-Net
Feb 9, 2020·International Journal of Environmental Research and Public Health·Jing WuWenjie Sun
Feb 23, 2020·JAMA : the Journal of the American Medical Association·John E L WongChorh Chuan Tan
Feb 23, 2020·Clinical and Translational Medicine·Jun SheYuanlin Song
Feb 23, 2020·Radiology·Zi Yue ZuLong Jiang Zhang
Feb 23, 2020·BMJ : British Medical Journal·Pauline VetterLaurent Kaiser
Feb 25, 2020·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Anita PatelUNKNOWN 2019-nCoV CDC Response Team
Feb 28, 2020·European Journal of Immunology·Mirae ParkPeter J M Openshaw
Feb 28, 2020·Emerging Microbes & Infections·Weilie ChenXiaoping Tang
Feb 23, 2020·Journal of Medical Virology·Silvia AngelettiMassimo Ciccozzi
Feb 26, 2020·Journal of Clinical Medicine·Péter BoldogGergely Röst
Feb 29, 2020·The New England Journal of Medicine·Wei-Jie GuanUNKNOWN China Medical Treatment Expert Group for Covid-19
Feb 14, 2020·Singapore Medical Journal·Lionel Hon Wai Lum, Paul Anantharajah Tambyah
Mar 3, 2020·Emerging Infectious Diseases·Takeshi ArashiroAkira Nakamura
Mar 3, 2020·Clinical Chemistry and Laboratory Medicine : CCLM·Giuseppe Lippi, Mario Plebani
Mar 4, 2020·Intensive Care Medicine·Yaseen M ArabiSteve Webb
Mar 5, 2020·AJR. American Journal of Roentgenology·Yan Li, Liming Xia

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bronchoalveolar lavage

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