Clinical features of patients with acute coronary syndrome during the COVID-19 pandemic.

Journal of Thrombosis and Thrombolysis
Kensuke MatsushitaOlivier Morel

Abstract

Although a reduction in hospital admissions of acute coronary syndromes (ACS) patients has been observed globally during the coronavirus disease 2019 (COVID-19) pandemic, clinical features of those patients have not been fully investigated. The aim of the present analysis is to investigate the incidence, clinical presentation, and outcomes of patients with ACS during the COVID-19 pandemic. We performed a retrospective analysis of consecutive patients who were admitted for ACS at our institution between March 1 and April 20, 2020 and compared with the equivalent period in 2019. Admissions for acute myocardial infarction (AMI) reduced by 39.5% in 2020 compared with the equivalent period in 2019. Owing to the emergency medical services (EMS) of our region, all time components of ST-elevated myocardial infarction care were similar during the COVID-19 outbreak as compared with the previous year's dataset. Among the 106 ACS patients in 2020, 7 patients tested positive for COVID-19. Higher incidence of type 2 myocardial infarction (29% vs. 4%, p = 0.0497) and elevated D-dimer levels (5650 μg/l [interquartile range (IQR) 1905-13,625 μg/l] vs. 400 μg/l [IQR 270-1050 μg/l], p = 0.02) were observed in COVID-19 patients. In sum, a signific...Continue Reading

References

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Jul 18, 2020·Journal of the American College of Cardiology·Fizzah A ChoudryDaniel A Jones
Jul 23, 2020·Journal of Thrombosis and Thrombolysis·Benjamin MarchandotOlivier Morel
Aug 1, 2020·Journal of Thrombosis and Thrombolysis·Panayotis K VlachakisIoannis Kanakakis

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Citations

Jun 3, 2021·Journal of Clinical Medicine·Antonin TrimailleOlivier Morel
Aug 9, 2021·Stem Cell Reviews and Reports·Kyle ErnzenMing-Tao Zhao

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