Clinical features of the dilated phase of hypertrophic cardiomyopathy in comparison with those of dilated cardiomyopathy.

Clinical Cardiology
Tomoyuki HamadaYoshinori L Doi

Abstract

Although the dilated phase of hypertrophic cardiomyopathy (D-HCM) characterized by left ventricular (LV) systolic dysfunction and cavity dilatation has been reported to be a poor prognosis, this is now in contrast to the improved prognosis of dilated cardiomyopathy (DCM) in the era of advancements in heart failure management. There has been no investigation of the clinical features of D-HCM compared with those of DCM from the point of management of systolic dysfunction. The aim of this study was to investigate the clinical features of D-HCM in comparison with those of DCM in a single institute. We studied 20 consecutive patients with D-HCM (global ejection fraction < 50%) and 115 consecutive patients with DCM. At diagnosis of D-HCM, 8 (40%) of the D-HCM patients already experienced dyspnea (New York Heart Association [NYHA] class >or= III). Left atrial diameter was larger and prevalence of atrial fibrillation was higher in the D-HCM group, although LV size was larger and LV ejection fraction was lower in the DCM group. During the follow-up period (4.0 years), 11 (55%) of the patients with D-HCM died. The 5-year survival rate from all-cause mortality including cardiac transplantation was 45.6% in patients with D-HCM vs 81.6% in ...Continue Reading

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Citations

Jun 19, 2015·International Heart Journal·Masataka YoshinagaHideo Izawa
Apr 17, 2014·Journal of cardiology·Mareomi HamadaYuji Shigematsu
Oct 27, 2017·The International Journal of Cardiovascular Imaging·Sainan ChengShihua Zhao
Jan 26, 2018·Journal of Cardiovascular Development and Disease·Jennifer EnglandCatrin Sian Rutland
Jan 16, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Toru KuboHiroaki Kitaoka
Jan 5, 2019·BMC Cardiovascular Disorders·Nattakorn SongsirisukSarinya Puwanant
Jun 3, 2021·Journal of Clinical Medicine·Angita JainDeLisa Fairweather
Aug 3, 2021·Disease Models & Mechanisms·Ekaterina MigunovaEdward B Dubrovsky

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