Clinical findings of multiple pregnancy with a complete hydatidiform mole and coexisting fetus

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Si Won LeeYi Kyeong Chun

Abstract

The aim of this series was to evaluate the clinical features, management, and outcomes of multiple pregnancy with a complete hydatidiform mole and coexisting fetus (CHMCF). Between 1998 and 2008, we investigated 6 women with a diagnosis of a CHMCF. The gestational age at diagnosis, symptoms, serum b-human chorionic gonadotropin levels, cytogenetic and molecular analysis findings, complications, routes of delivery, and pregnancy outcomes were assessed. All cases were diagnosed before 14 weeks' gestation by sonography. Only 1 ended with the delivery of a live-born neonate, whereas the other 5 cases required termination of pregnancy (TOP) before 21 weeks' gestation because of severe maternal complications (eg, preeclampsia, thyrotoxicosis, lung metastasis, and heavy bleeding) or intrauterine fetal death. The pathologic diagnosis of a complete hydatidiform mole was confirmed in all cases. Two patients required methotrexate for treatment of persistent trophoblastic disease (PTD). On the basis of our experience, in cases with a normal karyotype and no gross fetal abnormalities on sonography, we carefully recommend continuation of pregnancy as long as maternal complications are absent or controllable. However, updated treatment criter...Continue Reading

References

Sep 1, 1991·Obstetrical & Gynecological Survey·L O Vejerslev
Dec 1, 1996·Obstetrical & Gynecological Survey·R E BristowF R Witter
Mar 1, 1997·American Journal of Obstetrics and Gynecology·E JauniauxK H Nicolaides
Apr 25, 2003·American Journal of Obstetrics and Gynecology·Joseph R WaxAngelina Cartin
Dec 3, 2003·The Journal of Obstetrics and Gynaecology Research·Kimiyo TakagiShigeru Saito
May 18, 2004·Acta Obstetricia Et Gynecologica Scandinavica·Neelam AggarwalKala Vasishta
Dec 15, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Pascale MarcorellesNicole Lagarde
Oct 9, 2008·The Journal of Obstetrics and Gynaecology Research·Cheol Hong KimTae-Bok Song

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Citations

Mar 26, 2016·Clinical Case Reports·Ariel PolonskyEddie Fridman
Mar 10, 2020·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Sujata SiwatchG R V Prasad
Apr 5, 2013·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·S DalmiaA M Coady
Sep 23, 2014·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Y HeD-Z Li
Apr 28, 2020·BJOG : an International Journal of Obstetrics and Gynaecology·N Zilberman SharonE Jauniaux
Nov 19, 2014·Journal of Obstetrics and Gynaecology of India·Sunil K BajajBrij Bhushan Thukral
Dec 29, 2013·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Maria OkumuraMarcelo Zugaib

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