Clinical guidelines. Labor induction abortion in the second trimester

Contraception
Lynn BorgattaSociety of Family Planning

Abstract

Labor induction abortion is effective throughout the second trimester. Patterns of use and gestational age limits vary by locality. Earlier gestations (typically 12 to 20 weeks) have shorter abortion times than later gestational ages, but differences in complication rates within the second trimester according to gestational age have not been demonstrated. The combination of mifepristone and misoprostol is the most effective and fastest regimen. Typically, mifepristone 200 mg is followed by use of misoprostol 24-48 h later. Ninety-five percent of abortions are complete within 24 h of misoprostol administration. Compared with misoprostol alone, the combined regimen results in a clinically significant reduction of 40% to 50% in time to abortion and can be used at all gestational ages. However, mifepristone is not widely available. Accordingly, prostaglandin analogues without mifepristone (most commonly misoprostol or gemeprost) or high-dose oxytocin are used. Misoprostol is more widely used because it is inexpensive and stable at room temperature. Misoprostol alone is best used vaginally or sublingually, and doses of 400 mcg are generally superior to 200 mcg or less. Dosing every 3 h is superior to less frequent dosing, although i...Continue Reading

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Nov 12, 2019·Dr. Aya Mohr-Sasson

References

Oct 1, 1992·American Journal of Obstetrics and Gynecology·J OwenS E Gray
Apr 1, 1991·British Journal of Obstetrics and Gynaecology·K J Thong, D T Baird
Feb 17, 1984·JAMA : the Journal of the American Medical Association·M E KafrissenW Cates
Nov 1, 1994·American Journal of Obstetrics and Gynecology·H W LawsonM Ramick
Jan 1, 1993·Gynecologic and Obstetric Investigation·A BugalhoS Bergström
Aug 1, 1993·British Journal of Obstetrics and Gynaecology·K J Thong, D T Baird
Jul 1, 1996·British Journal of Obstetrics and Gynaecology·D WebsterA Templeton
Jul 1, 1996·American Journal of Obstetrics and Gynecology·J K Jain, D R Mishell
Apr 1, 1996·European Journal of Obstetrics, Gynecology, and Reproductive Biology·K PhillipsA M Mathers
Aug 1, 1996·The Australian & New Zealand Journal of Obstetrics & Gynaecology·R J Armatage, M J Luckas
Nov 1, 1996·European Journal of Obstetrics, Gynecology, and Reproductive Biology·E G YaparO Gökmen
Jul 2, 1999·Obstetrics and Gynecology·A ElimianN Tejani
May 20, 2000·American Journal of Obstetrics and Gynecology·E A DreyP D Darney
Jun 1, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·T K Al-Hussaini
Sep 20, 2001·The Journal of Obstetrics and Gynaecology Research·Y HerabutyaP Punyavachira
Nov 13, 2001·Obstetrics and Gynecology·L BerghahnS Droste
Dec 1, 2001·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·W M Hern
Jan 15, 2002·The Australian & New Zealand Journal of Obstetrics & Gynaecology·A Gilbert, R Reid
Feb 1, 2002·Human Reproduction·Oi Shan TangPak Chung Ho
Mar 21, 2002·American Journal of Obstetrics and Gynecology·Jan E Dickinson, Sharon F Evans

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Citations

Jan 21, 2014·Journal de gynécologie, obstétrique et biologie de la reproduction·M Pluchon, N Winer
May 9, 2014·Obstetrics and Gynecology·Alisa B Goldberg
Dec 25, 2012·Contraception·Nathalie KappDalia Brahmi
Dec 1, 2012·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Umran Küçükgöz GüleçSelim Buyukkurt
Sep 19, 2015·Taiwanese Journal of Obstetrics & Gynecology·Wan-Hua TingSheng-Mou Hsiao
Jun 14, 2012·The Journal of Obstetrics and Gynaecology Research·Saipin Pongsatha, Theera Tongsong
Sep 22, 2016·Journal of Obstetrics and Gynaecology of India·Prasanna Latha Akkenapally
Aug 6, 2015·Journal of Obstetrics and Gynaecology of India·Deepika NautiyalNavnita Banerjee
May 1, 2016·Contraception·Mitchell D Creinin, Melissa J Chen
May 22, 2016·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Dustin CostescuMatthew Reeves
Nov 3, 2016·Current Opinion in Obstetrics & Gynecology·Kate A Shaw, Klaira Lerma
Mar 12, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Melih VelipasaogluHuseyin Mete Tanir
Aug 24, 2017·BJOG : an International Journal of Obstetrics and Gynaecology·K A ShawP D Blumenthal
Sep 20, 2018·Journal of Feline Medicine and Surgery·Serhan Serhat AyMurat Fındık
Mar 31, 2012·Journal of Biosocial Science·Jeffrey EdmeadesAnju Malhotra
Feb 15, 2019·The Journal of Obstetrics and Gynaecology Research·Misooja LeeTadashi Kimura
Oct 2, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sergey V BarinovOksana V Lazareva
Jun 7, 2017·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Sarita SonalkarAngela Y Chen
Apr 21, 2019·Advances in Therapy·Jessika A Ralph, Lee P Shulman
Aug 20, 2016·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Martine D FreemanAssaf Ben-Meir
Jun 11, 2019·Journal of Obstetrics and Gynaecology of India·Alka A Mukherjee
Feb 23, 2020·Obstetrics and Gynecology
Sep 19, 2017·Current Opinion in Obstetrics & Gynecology·Klaira Lerma, Kate A Shaw
Dec 18, 2020·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Limei WuJiayin Zhang
Jul 30, 2021·Clinical Obstetrics and Gynecology·Megan A CohenAlison Edelman

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