Clinical implementation of kilovoltage cone beam CT for the verification of sequential and integrated photon boost treatments for breast cancer patients.

The British Journal of Radiology
E M DonovanEmma J Harris

Abstract

The objective of this study was to formulate a practical method for the use of cone beam CT (CBCT) for the verification of sequential and integrated tumour bed boosts for early breast cancer patients. Partial arc scan geometries were assessed on a treatment unit. Imaging dose measurements on an Elekta Synergy CBCT system were made in a CT dose phantom for scan parameters 100 kV, 25 mA and 40 ms with an S20 collimator. The protocol was used to verify the setup of a cohort of 38 patients, all of whom had surgical clips inserted in the tumour bed. Setup errors with and without an extended no action level (eNAL) protocol were calculated. Arcs from 260° to 85° (left breast) and 185° to 15° (right breast) were found sufficient to image fiducial markers and anatomy whilst accounting for the physical limits of the equipment. A single treatment and imaging isocentre was found by applying simple constraints: isocentre <8 cm from midline and isocentre-couch distance <30 cm. Contralateral breast doses were ∼2 mGy per scan (right breast) and ∼12 mGy (left breast). Both mean population systematic error and mean population random error were 3 mm prior to correction. The systematic error reduced to 1.5 mm using an eNAL correction protocol, imp...Continue Reading

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Citations

Feb 13, 2016·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Thomas MulliezLiv Veldeman
Jun 4, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Frederick R BartlettAnna M Kirby
Mar 6, 2015·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Frederick R BartlettAnna M Kirby
Oct 5, 2016·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Juan-Francisco Calvo-OrtegaJoan Casals
Oct 21, 2016·The British Journal of Radiology·Nicolle DunkerleyEllen M Donovan
Mar 1, 2017·Australasian Physical & Engineering Sciences in Medicine·Deepak BasaulaLois Holloway
Oct 10, 2021·Radiology and Oncology·Elham PiruzanHojjat Mahani

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