Clinical implications of intravesical recurrence after radical nephroureterectomy for upper urinary tract urothelial carcinoma

International Journal of Urology : Official Journal of the Japanese Urological Association
Shinichi YamashitaYoichi Arai

Abstract

To characterize the site and clinical implications of intravesical recurrence after radical nephroureterectomy for upper urinary tract urothelial carcinoma. Patients who underwent radical nephroureterectomy for upper urinary tract urothelial carcinoma between 2000 and 2011 at 12 institutions participating in the Tohoku Urological Evidence-Based Medicine Study Group were included in the present study. Those who underwent prior or simultaneous radical cystectomy were excluded. The site of intravesical recurrence was investigated, and the survival curves after radical nephroureterectomy were analyzed retrospectively using the Kaplan-Meier method. Multivariate analyses of factors predicting survival were carried out. A total of 534 patients were eligible for the present study. With a median follow up of 47 months, 205 patients (38.4%) had intravesical recurrence. The intravesical recurrence-free survival rates at 1, 2, and 5 years were 74.6%, 62.5% and 56.3%, respectively. In a subset of 137 patients with intravesical recurrence who did not have bladder cancer before or at the diagnosis of upper urinary tract urothelial carcinoma, the most frequent site of intravesical recurrence was around the cystotomy (52.6%), followed by at the...Continue Reading

References

Nov 16, 2004·The Journal of Urology·Simon V BariolDavid A Tolley
Jan 27, 2009·Journal of Surgical Oncology·Frederick L Greene, Leslie H Sobin
Mar 26, 2013·International Journal of Urology : Official Journal of the Japanese Urological Association·Vincent ElaloufMarc Zerbib
Apr 30, 2013·International Journal of Urology : Official Journal of the Japanese Urological Association·Bogomir Milojevic
Sep 6, 2013·Japanese Journal of Clinical Oncology·Akihiro ItoUNKNOWN Tohoku Urological EBM Study Group

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Citations

Sep 16, 2019·International Journal of Urology : Official Journal of the Japanese Urological Association·Shingo Hatakeyama, Chikara Ohyama
May 14, 2019·International Journal of Urology : Official Journal of the Japanese Urological Association·Satoshi YamamotoTomohiko Ichikawa
Apr 3, 2019·International Urology and Nephrology·Bogomir MilojevicSandra Sipetic Grujicic

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