Abstract
The electrocardiogram (ECG) remains a simple, universally available, and prognostically powerful investigation in heart failure, and acute coronary syndromes. We sought to assess the prognostic utility of clinical, angiographic, and simple ECG parameters in a large cohort of patients undergoing elective cardiac catheterization (CC) for known or suspected coronary artery disease. Consecutive consenting patients undergoing CC for coronary disease were enrolled at a single tertiary center. Patient data, drug therapy, catheter reports, and ECG recordings were prospectively recorded in a validated electronic archive. The primary outcome measure was death or nonfatal myocardial infarction (MI) over 1 year or until percutaneous or cardiac surgical intervention. Independent prognostic markers were identified using the Cox proportional hazard model. A total of 682 individuals were recruited of whom 17(2.5%) died or suffered a nonfatal MI in 1 year. In multivariate analysis QRS duration (ms) (HR 1.03 95% CI 1.01-1.05, P = 0.003), extent of coronary disease (HR 2.01 95% CI 1.24-3.58, P = 0.006), and prolonged corrected QT peak interval in lead I (HR 1.02 95% CI 1.00-1.03, P = 0.044) were independently associated with death or nonfatal MI....Continue Reading
References
Oct 1, 1991·Circulation·E G SchoutenJ Pool
Jan 1, 1991·The American Journal of Cardiology·R J GoldbergD Levy
Jan 1, 1990·Diabetic Medicine : a Journal of the British Diabetic Association·D J Ewing, J M Neilson
Jan 1, 1990·Journal of Clinical Epidemiology·R W PetersS Yusuf
Jul 1, 1986·European Heart Journal·D J SheridanW J Penny
May 1, 1983·Circulation·D A BramletF R Cobb
Sep 1, 1982·Circulation·M B MockT Killip
Feb 1, 1995·Journal of the American College of Cardiology·P M OkinP Kligfield
May 15, 1994·The American Journal of Cardiology·P M RautaharjuC D Furberg
Dec 1, 1993·American Heart Journal·A MichaelidesH Boudoulas
Aug 19, 1997·Circulation·A Melgarejo-MorenoJ Allegue-Gallego
Nov 24, 1998·Pacing and Clinical Electrophysiology : PACE·I SavelievaM Malik
Dec 5, 1998·Annals of Internal Medicine·A S GoA L Avins
Mar 30, 1999·Circulation·D A KassE Nevo
Jun 8, 2000·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·A A CantorR Ilia
Mar 10, 2001·Journal of Cardiovascular Electrophysiology·M A WatanabeA Karma
Mar 28, 2001·Progress in Cardiovascular Diseases·M M BednarJ N Ruskin
Apr 25, 2001·Diabetic Medicine : a Journal of the British Diabetic Association·P RossingH H Parving
Jul 7, 2001·European Heart Journal·L JordaensUNKNOWN MIRRACLE Investigators
Jul 13, 2001·The American Journal of Cardiology·H SilvetR G Pai
May 4, 2002·The American Journal of Cardiology·Emmanouil S BrilakisIan P Clements
Jun 21, 2002·American Heart Journal·Stephen IulianoUNKNOWN Department of Veterans Affairs Survival Trial of Antiarrhythmic Therapy in Congestive Heart Failure
Apr 1, 2003·Circulation·Bojan VrtovecBranislav Radovancevic
May 28, 2003·International Journal of Cardiology·K Y K WongT M MacDonald
Oct 1, 2003·The American Journal of Cardiology·Tamara HorwichLeslie Saxon
May 17, 2005·Heart·G Y ShinA S Breathnach
Dec 13, 2005·European Heart Journal·Axel BauerGeorg Schmidt
Apr 25, 2006·Hearing Research·Hai-Tao WangLin Chen