Clinical importance of F-waves as a prognostic factor in Guillain-Barré syndrome in children

Korean journal of pediatrics
Eung-Bin LeeSae Yoon Kim

Abstract

A limited number of studies have examined the link between F-wave abnormalities and clinical presentation in pediatric Guillain-Barré syndrome (GBS). Therefore, this study examined the importance of F-wave abnormalities as a prognostic factor in pediatric GBS patients. The records and electrodiagnostic studies (EDS) of 70 GBS patients were retrospectively evaluated, and divided into 2 groups according to the results of EDS. Group A (n=33) presented with F-wave abnormalities, and group B (n=26) exhibited normal findings. We compared laboratory reports, clinical features, response to treatment, and prognosis between the 2 groups. Motor weakness was the most frequently observed symptom for either group. Clinically, the incidence of fever and upper respiratory symptoms differed between the 2 groups, while the prevalence of abnormal deep tendon reflex (DTR) was significantly higher in group A than B (P<0.05). Patients diagnosed with GBS had received intravenous immunoglobulin treatment: 94% in group A and 58% in group B. Furthermore, significantly greater numbers of patients in group A showed H-reflex abnormalities and poor prognosis compared with group B (P<0.05). This study demonstrated that F-waves are a clinically important prog...Continue Reading

References

Feb 1, 1980·Journal of Neurology, Neurosurgery, and Psychiatry·T LachmanR R Young
Jan 25, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·S KuwabaraN Yuki
Jul 13, 2002·Muscle & Nerve. Supplement·Christian Bischoff
Apr 23, 2004·Journal of Neuroscience Methods·A RainoldiI Caruso
Aug 26, 2004·Neuropsychologia·T Edward ReedAndrew M Johnson
Jan 11, 2005·Neurophysiologie clinique = Clinical neurophysiology·F Mesrati, M F Vecchierini
Dec 13, 2006·Annals of Saudi Medicine·Ahmed S M NadeemFakir Al-Ani
Mar 6, 2007·TheScientificWorldJournal·Morris A Fisher
Oct 14, 2008·Lancet Neurology·Pieter A van DoornBart C Jacobs
Apr 17, 2010·Journal of Clinical Immunology·Pieter A van DoornBart C Jacobs
Nov 22, 2011·Revue neurologique·F C WangO Bouquiaux
May 9, 2012·Journal of Neurology, Neurosurgery, and Psychiatry·Yusuf A Rajabally, Antonino Uncini
Sep 12, 2015·Neuropsychiatric Disease and Treatment·Murat Alemdar

❮ Previous
Next ❯

Citations

Apr 30, 2019·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Reda Badry
Jul 6, 2019·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Rishi SharmaRuple S Laughlin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.