PMID: 6412796Sep 10, 1983Paper

Clinical importance of reversibility in primary goitrous hypothyroidism

British Medical Journal
M YoshinariT Omae

Abstract

Twenty seven hypothyroid patients with a serum concentration of thyroid stimulating hormone (TSH) of over 40 mU/1 were followed up for three to 20 weeks without replacement therapy. The serum thyroid hormone concentrations increased with a dramatic decrease in serum TSH values in 14 patients (reversible group) but there was no significant change in the other 13 (irreversible group). Fourteen out of 19 patients with goitre but none of the eight patients without goitre belonged to the reversible group. All of the 11 patients with a high uptake of iodide by the thyroid, three of the six with a normal uptake, and none of the 10 with a low uptake belonged to the reversible group. These observations indicate that patients with goitrous hypothyroidism with a preserved thyroid uptake of iodide are likely to become euthyroid spontaneously without replacement therapy.

References

May 1, 1975·The Journal of Pediatrics·M L RallisonF H Tyler
Jun 1, 1978·Annals of Internal Medicine·T Yamamoto, H Sakamoto
Aug 1, 1977·Annals of Internal Medicine·N AminoY Kumahara
Jun 26, 1969·The New England Journal of Medicine·J A PittmanR J Beschi
Apr 1, 1971·The Journal of Clinical Endocrinology and Metabolism·L E BravermanF Maloof
May 1, 1970·The Journal of Clinical Endocrinology and Metabolism·T H OddieC S Thompson
May 1, 1966·Archives of Surgery·D K WeaverJ G Batsakis
Apr 8, 1982·The New England Journal of Medicine·N AminoK Miyai
Dec 1, 1980·Archives of Internal Medicine·H E Carlson
Aug 1, 1965·Archives of Internal Medicine·C WATANAKUNAKORNT C EVANS

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Citations

Aug 1, 1988·Baillière's Clinical Endocrinology and Metabolism·N Amino
Aug 1, 1988·Baillière's Clinical Endocrinology and Metabolism·P J Leslie, A D Toft
Jul 21, 1994·The New England Journal of Medicine·A D Toft
Jun 9, 2001·Thyroid : Official Journal of the American Thyroid Association·K MarkouA G Vagenakis
Dec 1, 1989·Postgraduate Medical Journal·M CoffernilsJ Unger
Jan 1, 1989·The American Journal of the Medical Sciences·T F Nikolai
Apr 1, 1989·Journal of the American Geriatrics Society·K OkamuraM Fujishima
Nov 1, 1995·The American Journal of Medicine·B PérezD Alarcón-Segovia
Feb 1, 1991·Clinical Endocrinology·A D Toft
Dec 1, 1989·Postgraduate Medical Journal·D A Walsh, T C O'Shaughnessy
Jun 20, 2014·Human Reproduction Update·Martina ColicchiaCostanzo Moretti
Aug 1, 1985·Archives of Disease in Childhood·S R Stern, C J Kelnar
Sep 1, 1984·Scandinavian Journal of Clinical and Laboratory Investigation·R JanssonA Karlsson
Oct 30, 2003·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Clifford D ClarkMark R Burge

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