Clinical improvement following home parenteral nutrition in pediatric patients with intestinal failure

Journal of the Formosan Medical Association = Taiwan Yi Zhi
Yi-Ching TungMei-Hwei Chang

Abstract

Home parenteral nutrition (HPN) is being increasingly used to treat children with intestinal failure. This study evaluated the long-term growth, outcome and complications in Taiwanese pediatric patients with intestinal failure who were treated with HPN. This retrospective study included 27 consecutive pediatric patients with intestinal failure who received long-term HPN between 1987 and 2002. These patients were categorized into two groups according to whether they had short bowel syndrome or a bowel motility disorder. Growth, prognosis and complications, including cholestasis, hypoglycemia, hyperglycemia and infections were compared between the two groups. The median age of starting HPN was significantly younger in patients with short bowel syndrome (5 months) than in patients with motility disorders (1.9 years). The median duration of HPN treatment in the overall group was 13.5 months (range, 2.1-113.1 months); weight and height increased 1.7 +/- 2.3 and 1.0 +/- 1.6 in z score, respectively. The most common complications were cholestatic liver disease (52%), hypoglycemia (15%) and hyperglycemia (33%). All patients maintained stable serum glucose levels at follow-up. Cholestatic liver disease developed after 2.3 +/- 2.0 months...Continue Reading

References

Oct 14, 2000·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·V ColombC Ricour
Mar 22, 2001·Archives of Disease in Childhood·J W Puntis
Apr 16, 2002·Current Opinion in Clinical Nutrition and Metabolic Care·Manila CandussoNatale Dodaro
May 15, 2002·JPEN. Journal of Parenteral and Enteral Nutrition·Carol E SmithLyn Howard
May 23, 2003·Gastroenterology·Lyn Howard, Christopher Ashley

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Citations

Jan 1, 2008·JPEN. Journal of Parenteral and Enteral Nutrition·Vered KakzanovAnthony K C Chan
Feb 3, 2009·The British Journal of Nutrition·Carmina Wanden-BergheUNKNOWN Red de Malnutrición en Iberoamérica - Ciencia y Tecnología para Desarrollo (Red MeI - CYTED)
Mar 29, 2018·International Journal of Integrated Care·Esther SuterGiselda Quintana Marques

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