Clinical influences on bone cement monomer release

Journal of Biomedical Materials Research
S C BayneP R Meyer


Monomer losses for two self-curing acrylic cements were similar via laboratory serial weighing experiments. Both the P/L ratio and mixing duration substantially influenced subsequent monomer losses, but ambient temperature variation during mixing had little effect. Greater losses were encountered during the mixing and setting intervals than during the molding interval. Patient potential exposure to monomer occurs during the molding and setting intervals; therefore, handling procedures reducing losses in these intervals are important to the surgeon. The least monomer loss during both molding and setting occurred at the manufacturers' recommended P/L ratio, which strongly indicated the need to mix all contents supplied. Mixing loss increased with amount of spatulation. However, once the mass was well mixed (about 300 steady spatulations), no further decreases in the molding and setting interval losses were promoted by overmixing. Because of the lower monomer loss rate during the molding interval, postponed cement insertion may not be warranted in light of losing mechanical locking efficiency. The actual ramifications of a threefold reduction in potential patient exposure (3.5 down to 1.2 wt% of total monomer) via modified handlin...Continue Reading


Jan 1, 1975·Journal of Biomedical Materials Research·S C BayneR Wildes
Mar 1, 1972·Anesthesiology·A F Newens, R G Volz
Oct 14, 1972·British Medical Journal·D CadleC C Wilmshurst
Oct 28, 1972·British Medical Journal·P ColeD Dandy
Nov 1, 1971·Anesthesiology·C A Cohen, T C Smith
Aug 8, 1970·British Medical Journal·J N PowellP Hill
Jan 9, 1971·The Medical Journal of Australia·B BlochG W Hastings
Aug 1, 1971·British Medical Journal·H PhillipsA W Lettin


Jan 1, 1979·Journal of Biomedical Materials Research·C M SchoenfeldE P Lautenschlager
Nov 16, 2004·The Orthopedic Clinics of North America·L Lidgren, Otto Robertson

Related Concepts

Skeletal Bone
Bone Cements
Dental Cement Material

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.